Department of Internal Medicine
Pulmonary, Critical Care and
Occupational Medicine Faculty
Medical School:
Duke University
Residency:
University of Washington
University of Colorado
Fellowship:
University of Colorado
D. Michael Shasby, M.D.
Professor
Dr. Shasby's research examines the acute inflammatory response and how it affects lung endothelial and epithelial surfaces. His current work focuses on cell adhesion molecules and how their function is altered by inflammatory agonists such as histamine. His clinical interests are in critical care, bronchoscopy and asthma.
Honors, Awards, and Organizations
- Alpha Omega Alpha
- Diplomate, American Board of Internal Medicine, Pulmonary Diseases, and Critical Care Medicine
- American College of Chest Physicians
- American College of Physicians, Member
- American Heart Association Established Investigator Award
- American Society for Clinical Investigation
- American Thoracic Society
- Central Society for Clinical Research
- Veterans Administration, Clinical Investigator
- Phi Beta Kappa
- Association of American Physicians
Recent Publications
- Michael C Winter, Sandra S Shasby, Dana R. Ries and D Michael Shasby. PAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta agonists. Am J Physiol, Lung Cellular and Molecular Physiology 291:L628-L635, 2006.
- Alicia L. Humlicek, Lori J. Manzel, Cecilia L. Chin, Lei Shi, Katherine J. D. A. Excoffon, Michael C. Winter, D. Michael Shasby, and Dwight C Look. Paracellular Permeability Restricts Airway Epithelial Responses to Selectively Allow Activation by Mediators at the Basolateral Surface. The Journal of Immunology 178:6395-6403, 2007.
- Michael C Winter, Sandra Shasby, D. Michael Shasby. Compromise of E-cadherin-mediated adhesion and epithelial barrier function following activation of G-protein coupled receptors is rescued by Y to F mutations in beta-catenin Am J Physiol, Lung Cellular and Molecular Physiology 294:L442-448, 2008.