Department of Internal Medicine
Clinical Pharmacology Faculty
Medical School:
University of Sheffield,
England
Residency:
Leicester Royal Infirmary,
Leicester, England
Hope Hospital,
Salford, England
Fellowship:
University of Edinburgh,
Scotland
William G. Haynes, M.B.Ch.B., M.R.C.P., M.D.
Clinical Professor and Division Director
Director, General Clinical Research Center
Dr. Haynes' research interests include studies of the effects of homocysteine, diabetes, hypertension and hyperlipidemia on endothelial function in humans. He is also interested in the cardiovascular and autonomic effects of obesity, focusing on novel mediators such as leptin and the melanocortins. Dr. Haynes has a particular interest in vascular medicine, focusing on prevention and regression of atherosclerosis through management of cardiovascular risk factors including hyperlipidemia, hypertension and high homocysteine.
Honors, Awards, and Organizations
- Medical Research Society, Member
- British Hypertension Society, Member
- International Society for Hypertension, Member
- British Pharmacology Society, Member
- American Heart Association Council on Circulation, Fellow
American Heart Association, Council for High Blood Pressure Research, Fellow
American Physiological Society, Member - Medical Research Society Young Investigator Prize, 1994
- Caledonian Clinical Pharmacology Society Young Investigator Prize, 1994
- American Heart Association Council for High Blood Pressure Research Merck Young Investigator Prize, 1994
- Royal Society of Medicine Derrick Dunlop Traveling Fellowship, 1994
- Young Scholar Award, American Society of Hypertension, 1996
- Faculty Development Award, Pharmaceutical Research Manufacturers of America Foundation, 1997
- Austin Doyle Prize, International Society of Hypertension, 1998
Recent Publications
- Haynes, W.G., Hand, M.F., Dockrell, M.E.C., Eadington, D.W., Lee, M.R., Hussein, Z., Benjamin, N., Webb, D.J.: Physiological Role of Nitric Oxide in Regulation of Renal Function in Humans. Am. J. Physiol., 272 :F364-F371, 1997.
- Haynes, W.G., Morgan, D.A., Walsh, S.A., Mark, A.L., and Sivitz, W.I.: Receptor-Mediated Regional Sympathetic Nerve Activation by Leptin. J. Clin. Invest. 100 :270-278, 1997.
- Haynes, W.G., Morgan, D.A., Walsh, S.A., Sivitz, W.I., and Mark A.L.: Cardiovascular Consequences of Obesity: Role of Leptin. Clin. Exp. Pharmacol. Therap. 25:65-69, 1998.
- Haynes, W.G., Ferro, C.E., O'Kane, K., Somerville, D., Lomax, C.L., and Webb, D.J.: Systemic Endothelin Receptor Blockade Decreases Peripheral Vascular Resistance and Blood Pressure in Man. Circulation, 93 :1860-1870, 1996.
- Haynes, W.G., Strachan, F.E., and Webb, D.J.: Endothelin ETA and ETB Receptors Mediate Vasoconstriction of Human Resistance and Capacitance Vessels In Vivo . Circulation, 92 :357-363, 1995.
- Haynes, W.G., and Webb, D.J. 1994. Contribution of endogenous generation of endothelin-1 to basal vascular tone. Lancet, 344:852-854.
Links of Interest