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The Adult Blood and Marrow Transplantation Program


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Glossary - G


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Gallbladder: The pear-shaped organ that sits below your liver. Bile is stored in the gallbladder.

Gastrointestinal: Refers to the digestive tract and/or the intestines.

Gene: Collections of DNA segments in each cell that contains our hereditary information and determines the traits we get from past generations. There are approximately 30,000 genes in each human cell containing a nucleus.

General Anesthesia: This form of anesthesia causes people to lose consciousness. People undergoing general anesthesia are unaware of the surgical procedure or any other sensations.

Genetic: Inherited; having to do with information that is passed from parents to children through DNA that make up our genes.

GM-CSF: See Granulocyte-macrophage - colony stimulating factor

Grade: A way to rate the aggressiveness or malignancy of a tumor. The grade helps determine the best treatment for the cancer. The higher the grade, the more aggressive a tumor is.

Graft Failure: A condition that may happen after a stem cell transplant where the donated stem cells are present, but function very poorly or not at all.

Graft Rejection: A condition that may happen to people who receive someone else’s blood stem cells or marrow in a transplant. The patient experiences a loss of donor cells through an active (often the recipient’s immune system) process. It is most often seen in patients with aplastic anemia.

Graft vs. Host Disease (GVHD): A complication of stem cell transplantation in patients receiving stem cells from another person. The newly transplanted immune system identifies the patient’s body as foreign and attacks it, resulting in varying degrees of damage to three target organs: the skin, gastrointestinal tract, and liver.

Granulocyte: A type of white blood cell also called a neutrophil. These cells are important in fighting bacterial and fungal infections.

Granulocyte-macrophage - colony stimulating factor (GM-CSF): Sold as Sargramostim or Leukine, this growth factor is used like G-CSF to speed the recovery of the granulocyte count following the administration of chemotherapy.

Growth Factor: Another term used when referring to medications that stimulate the production of blood cells. Filgrastim is an example of a growth factor that stimulates granulocyte production. (See Filgrastim)