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Glossary - L


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Laminar Air Flow (LAF) room: A hospital room on the AB&MT Transplant Unit that is reserved for patients receiving a donor cell transplant This is a room-within-a-room with one wall of the interior room being a high efficiency filter providing the cleanest air possible for stem cell transplant patients.

Lesion: An area of abnormal tissue change.

Leukemia: Cancer originating in the blood forming organs or bone marrow. White blood cells are produced in excessive amounts and are unable to function properly. Common forms of leukemia include chronic or acute lymphocytic or granulocytic leukemia.

Leukocyte: Another name for white blood cells. A leukocyte is a type of cell in the blood which helps defend the body against diseases caused by bacteria, virus, or parasites. There are three types of leukocytes: monocytes, granulocytes and lymphocytes.

Leukocytosis: An increase in the total white blood cell count.

Leukopenia: A low number of white blood cells or a decrease in the total white blood cell count.

Leukopheresis: The process of separating some of the white blood cells from the rest of the blood. Blood is taken from the vein and some of the leukocytes are removed. The remaining blood cells are returned.

Lymph: A clear fluid that contains mostly lymphocytes and circulates through the body in the lymphatic system. It is drained from tissue spaces by the lymphatic system and can transport bacteria, viruses and cancer cells. The lymph channels eventually dump the lymph back into the blood stream.

Lymph Nodes: Small, oval-shaped glands distributed throughout the body that contain the vast majority of lymphocytes. These glands house lymphocytes and filter microorganisms and other particles from lymph. The function of these nodes is to fight infection.

Lymphadenectomy: A surgical procedure to selectively or totally remove lymph nodes in the armpit, pelvis, and/or groin. This procedure may be done to determine the spread of the cancer or to treat certain forms of cancer.

Lymphadenopathy: An enlargement of the lymph nodes caused by infection or cancer infiltration.

Lymphatic System: The tissues and organs that produce, store, and carry white blood cells that fight infection and disease. This system includes the bone marrow, spleen, thymus, and lymph nodes and a network of thin tubes that carry lymph and white blood cells. These tubes branch, like blood vessels, into all the tissues of the body.

Lymphedema: Swelling of a limb such as an arm. This can be caused by surgical removal of lymph nodes or obstruction or damage to lymph nodes.

Lymphoblast: An immature cell that develops into a lymphocyte.

Lymphocyte: One of the major groups of white blood cells. The three main kinds of lymphocytes are T cells, B cells, and Natural Killer cells. T cells attack and destroy virus-infected cells, foreign tissue and cancer cells. B cells help produce antibodies or proteins that help destroy foreign substances. Natural Killer cells destroy cancer cells and virus-infected cells.

Lymphoma: A type of cancer that originates in the lymphatic system from the malignant transformation of a lymphocyte. Lymphoma can involve other organs, such as the liver and spleen. Lymphomas are categorized as Hodgkin's and Non-Hodgkin's.