To: Associate Professor of Medicine
Division: Cardiology

Medical School:
University of Minnesota

Residency:
University of Minnesota

Fellowship:
Oregon Health Sciences University

Faculty Appointment:
University of Iowa, 1999-

Teaching

• Consistently rated as an excellent teacher by students, residents, fellows and peers
• Committed to teaching pertinent underlying physiology/pathophysiology as well as diagnostic and management issues of patient care
• Regularly mentors students, residents, and fellows in the Cardiology clinic, Cardiovascular Intensive Care Unit, the inpatient ward unit, the Cardiology consult service, and at the VAMC
• Participates in the teaching and mentoring of undergraduate students, graduate students, and research fellows in the laboratory setting
• Co-Director of the Summer Undergraduate MSTP Research (SUMR) Program
• Associate Director of the Cardiovascular Disease Fellowship Training Program

Scholarship/Professional Productivity

• Areas of research interest:
  • study of ion channels involved in sensation
  • working to understand the role of ASIC channels in cardiac sensation
  • worked to define the mechanisms by which modulatory proteins interact and regulate ASIC channels
• Independent research funding through the NIH
• Affiliate faculty member in the Neuroscience Graduate Program
• Invited to present work at local, national, and international meetings
• Manuscript reviewer for Annals of the New York Academy of Sciences, Basic Research in Cardiology, Neuroscience, American Journal of Physiology: Heart and Circulatory Physiology, the European Journal of Neuroscience, and Pain
• Grant reviewer for the National Science Foundation

Clinical and Administrative Service

• Co-director of the Summer Undergraduate MSTP Research (SUMR) Program
• Coordinates weekly Clinical Cardiology Conference
• Associate Director, Cardiovascular Disease Fellowship Training Program

Recent Publications

Benson, C.J., Xie, J., Wemmie, J.A., Price, M.P., Henss, J.M., Welsh, M.J., and Synder, P.M.: Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons. Proc. Natl. Acad. Sci. U.S.A, 99:2338-43, 2002.

Hruska-Hageman, A.M., Benson, C.J., Leonard, A.S., Price, M.P., and Welsh, M.J.: PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+-gated current. J. Biol. Chem. 279(45):46962-46968, 2004.

Price, M.P., Thompson, R.J., Eshcol, J.O., Wemmie, J.A., and Benson, C.J. : Stomatin modulates gating of ASIC channels. J. Biol. Chem. 279(51):53886-53891, 2004.

To: Professor of Medicine
Division: Gastroenterology and Hepatology

Medical School:
Wayne State University

Residency:
Johns Hopkins University

Fellowship:
The University of Iowa

Faculty Appointment:
The University of Iowa, 1993-

Teaching

• Consistently rated as an excellent to outstanding teacher by students, residents, fellows and peers
• Develops, directs, and provides lectures for courses and seminars at the college
• Instructs fellows, residents, and medical students in the diagnosis, pathophysiology, and treatment of many diseases on the UIHC Outpatient Gastroenterology Consult Service, the UIHC Inpatient Gastroenterology Consult Service, the Veterans Administration Hospital Gastroenterology Service, and GI outpatient clinic
• Teaches endoscopy skills (upper endoscopy, colonoscopy, polyp removal, dilatation, liver biopsy, variceal banding and percutaneous gastrostomy tube placement) to the GI fellows and surgical residents
• MSTP Clinical Connections Coordinator
• Develops and gives formal lectures for medical residents noon conference series, as well as the Applied Immunology Lecture Series for Internal Medicine Fellows
• Organizes the Gastroenterology Core Conference Series, the Research Conference schedule within the Division of Gastroenterology, and directs the GI/Hepatobiliary Journal Club
• Regular invited speaker at local, national, and international workshops and seminars

Scholarship/Professional Productivity

• Areas of research interest:
• immunoregulation of chronic inflammation
• mucosal inflammatory response
• Independent and collaborative funding from the NIDDK, NIH, Crohn’s and Colitis Foundation of America (CCFA), and the Broad Foundation
• Collaborates with other investigators
• Widely published in scholarly journals, including Journal of Immunology, Gastroenterology, FASEB Journal, American Journal of Physiology, and European Journal of Immunology
• Research reviewed in popular science magazines Science News (Washington, DC) and New Scientist (London, UK), newspapers including the London Times and the New York Times Science Section, and Time Magazine
• Holds a patent covering the use of helminthic parasites and their products for use in treating inflammatory bowel disease and other autoimmune disease

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Head, Gastroenterology Fellow Research Committee
• Director, Celiac Disease Clinic
• Director, Inflammatory Bowel Disease Center
• Active in regional patient education forums for IBD and Celiac Disease
• Medical Advisor for the Linn & Johnson Counties Celiac Disease Support Group and the Waterloo/Cedar Falls Celiac Disease Support Groups
• Member, Tissue Culture and Hybridoma Facility Oversight Committee
• Chaired the promotion review committee to evaluate assistant professors and non-tenured associate professors in the fall of 2001
• Served on the Department of Medicine Research Development Committee (chaired by Elizabeth Field) in 2001
• Served on the Internal Medicine research committee with Dr. Michael Welsh in 2004

Recent Publications

Ince, M.N., Elliott, D.E., Setiawan, T., Blum, A., Metwali, A., Wang, Y., Urban, J.F. Jr., and Weinstock, J.V. Cutting Edge: Heligmosomoides polygyrus Induces TLR4 on Murine Mucosal T Cells That Produce TGFb after Lipopolysaccharide Stimulation. J. Immunol. 176: 726-9, 2006

Elliott, D.E.,: “Intestinal Infections by Parasitic Worms”. W.B.Saunders. Sleisenger & Fordtran’s Gastrointestinal and Liver Disease 2006; Edition 8. Chapter 101.

Elliott D.E. R.W. Summers, and J.V.Weinstock. Helminths and the modulation of mucosal inflammation. Current Opinion in Gastroenterology 21: 51-58, 2005.

Summers, R.W., Elliott, D.E., Urban, J.F., Thompson, R. and Weinstock, J.V.: A Double-Blind Controlled Clinical Trial Using Trichuris Suis in Active Ulcerative Colitis. Gastroenterology 128:825-832, 2005.

Summers, R.W., Elliott, D.E., Urban, J.F., Jr., Thompson, R., and Weinstock, J.V. Trichuris suis Therapy in Crohn’s Disease. Gut, 54:87-90, 2005

Arsenescu, R., Blum, A.M., Metwali, A., Elliott, D.E., and J.V. Weinstock. IL-12 Induction of mRNA Encoding Substance P in Murine Macrophages from the Spleen and Sites of Inflammation. J Immunol. 174:3906-3911, 2005.

Elliott, D.E., Setiawan, T., Metwali, A., Blum, A., Urban, J.F. Jr., and Weinstock, J.V.: H. polygyrus Inhibits Established Colitis in IL10 Deficient Mice. Eur. J. Immunol. 34(10):2690-8, 2004

Blum, A.M., Metwali, A., Elliott, D.E., Berg, D.J.,and Weinstock, J.V.: CD4+ T cells from IL-10-deficient mice transfer susceptibility to NSAID-induced Rag colitis. Am. J. Physiology. 287:G320-5, 2004

Elliott, D.E. Expression and Function of Somatostatin and its Receptors in Immune Cells. In Somatostatin C.B. Srikant ed. (2004)

Weinstock, J.V., Summers, R. and Elliott, D.E.: Helminths and Harmony: Mounting Evidence Suggests that Helminths Help Regulate Mucosal Inflammation. (Commentary) Gut 53:7-9, 2004.

Qing, Z., Sewell, D., Elliott, D., Weinstock, J.V., Sandor, M., and Fabry, Z.: Helminth Ova Induce Protection from Experimental Autoimmune Encephalomyelitis. International Immunol. 15: 59-69, 2003.

Elliott, D. E., Li, J., Blum, A., Metwali, A, Qadir, K., Urban, J, Weinstock, J. V. Exposure to Schistosome Eggs Protects Mice from TNBS-induced Colitis. American J. Physiol. 284:G385-G391, 2003

Summers, R.W., Elliott, D. E., Qadir, K., Urban, Jr., J. F., Thompson, R., Weinstock, J. V.: Trichuris suis Appears Safe and Effective in the Treatment of Inflammatory Bowel Disease: A Possible Example of TH2 Conditioning of the Mucosal Immune Response. Am. J. Gastro. 98:2034-2041, 2003

To: Associate Professor of Clinical Medicine
Division: Pulmonary, Critical Care and Occupational Medicine

Medical School
University of Texas Medical Branch

Residency
University of North Carolina

Fellowship
The University of Iowa

Faculty Appointment
The University of Iowa, 1998-

To: Professor of Clinical Medicine
Division: Pulmonary, Critical Care and Occupational Medicine

Medical School
University College, Dublin

Residency
St. Vincent's Hospital, Dublin

Fellowship
The University of Iowa

Faculty Appointment
The University of Iowa, 1994-

Teaching

• Consistently rated as a very good to excellent teacher by students, residents, fellows and peers
• Teaches students, residents and pulmonary fellows in the management of patients with general and occupational pulmonary disorders
• Clinical preceptor for Occupational Medicine Residency at UIHC
• Participates in the structured teaching program for fellows in Pulmonary Division
• FCP III physical exam skills instructor
• Physician mentor for FCP IV students
• Invited speaker on campus, locally, and at regional occupational health meetings
• Serves as an external examiner in the Final Professional Examination in Medicine and Surgery for the National University of Ireland.

Scholarship/Professional Productivity

• Co-wrote the updated medical evaluation protocol for newly hired police officers and firefighters for the Municipal Fire and Police Retirement System of Iowa
• Co-investigator for a study evaluating the occurrence of occupational illness in former workers of the Iowa Army Ammunitions Plant in Middleton, Iowa
• Co-investigator in the UI Asthma Center

Clinical and Administrative Service

• Medical Director, Workers Health Clinic and University Employee Health Clinic
• Director, Occupational Medicine Section within the Division of Pulmonary Critical Care and Occupational Medicine
• Chair, Environment of Care Subcommittee at UIHC
• Member of a number of Hospital and University committees
• Represents UIHC on a regional planning group for hospital / EMS disaster and bioterrorism preparedness in Eastern Iowa

Representative Publications

Muller, B., Steelman, V., Hartley, P., and Casale, T.: An Approach Latex Allergy in the Health Care Worker. J Environmental Health, 1998.

Coxson, H.O., Hogg, J.C., Mayo, J.R., Behzad, H., Whittall, K. D.A., Hartley, P.G., Galvin, J.R., Wilson, J.S., and Hunninghake, Quantification of Idiopathic Pulmonary Fibrosis Using Computed Histology. American Journal of Respiratory and Critical Care Medicine, 155(5):1649-56, 1997.

Uppaluri R. Hoffman EA. Sonka M. Hartley PG. Hunninghake GW. Computer recognition of regional lung disease patterns. American Respiratory & Critical Care Medicine. 160(2):648-654, 1999.

Teaching:

• Consistently rated as an excellent teacher by students, residents, fellows and peers
• Taught the full continuum of learners: second and fourth year medical students, residents, fellows, faculty, and allied health care personnel
• Course Director, Biomedical Ethics Course
• Presented lectures in various departments at the College of Medicine, the VAMC, other Iowa communities, at the Scientific Meeting of the Iowa Chapter of the American College of Physicians, and at various national meetings
• Mentor and advisor for students and residents
• Recipient of Collegiate Teaching Award

Scholarship/Professional Productivity

• Areas of research interest:
• Biomedical ethics
• Principal Investigator funded by the Robert Wood Johnson Foundation
• Accepted to the NIA's Summer Institute on Aging Research, summer 2005
• Completed Ph.D. in ethics from Yale in December, 2004
• Editor, Law and Ethics Column of Johns Hopkins Advanced Studies in Medicine

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Member, UIHC Ethical Issues Subcommittee
• Faculty Representative, students’ Honor Council in the College of Medicine
• Member, Iowa Medical Society’s Committee on Law and Ethics
• Director, Program in Biomedical Ethics and Medical Humanities
• Reviewer for Journal of General Internal Medicine, Annals of Behavioral Medicine and
  Medical Care
• Reviewed workshop abstracts as a member of the Ethics & Humanities Workshop Selection Committee in preparation for the Society of General Internal Medicine’s
  28th Annual Meeting in New Orleans, LA
• Gave two brief interviews to Roy Justice on KXIC radio on end-of- life care and ethical decision-making, as well as an hour- long interview on medical error disclosure for WDEO in Michigan.
• Spoke about feeding tubes and end-of- life issues at Agudas Achim Congregation in Iowa City.
• Serves as an infectious disease consultant by telephone-to-ham radio for Dr. Gerard Rudy, a missionary physician in Ahuas, Honduras.

Recent Publications

Kaldjian LC, Jekel JK, Bernene JL, Rosenthal GE, Vaughan-Sarrazin M, Duffy TP. Internists' attitudes toward terminal sedation in end-of-life care. Journal of Medical Ethics 2004;30:499-503.

Kaldjian LC, Wu BJ, Kirkpatrick JN, Thomas-Geevarghese A, Vaughan-Sarrazin M. Medical house officers' attitudes toward vigorous analgesia, terminal sedation, and physician-assisted suicide. American Journal of Hospice & Palliative Medicine 2004;21:381-387.

Kaldjian LC, Weir RF, Duffy TP. A clinician's approach to clinical ethical reasoning. Journal of General Internal Medicine 2005;20:306-311.

Teaching

• Consistently rated as a very good to excellent teacher by students, residents, fellows and peers
• Presents lectures to incoming Nephrology fellows
• Presents CME lectures

Scholarship/Professional Productivity

• Areas of research interest:
  • clinical kidney and pancreas transplantation
  • Cardiovascular outcomes and mechanisms of progression of atherosclerosis in recipients of kidney transplant
  • New immunosuppressive regimens.
• Presented research at local and national meetings
• Funded by the National Kidney Foundation (Clinical Scientist Award)
• Principal Investigator or Co-P.I. for several clinical trials, including industry sponsored and investigator initiated clinical investigation, the NIH and NIDDK
• Supervises research of Trainees in Nephrology
• Mentored Patient-Oriented Clinical Project and Grant Applications
• Collaborates with other investigators
• Reviewer for the American Journal of Transplantation, Kidney International and American Journal of Kidney Diseases

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Staffs renal transplant clinics at the UIHC and the VAMC

Recent Publications

Pascual M, Curtis J, Delmonico F, Farrel L, Williams W, Kalil R, Jones P, Cosimi B, Tolkoff-Rubin N. A prospective, ramdomized trial of cyclosporine reduction in stable patients greater than 12 months after transplantation. Transplantation, 75, 1501-1505, 2003.

Kalil R, Dyer C, Rayhill SC : Long-term outcome of renal transplants from deceased donors correlates with the 30-day creatinine reduction ratio. American Journal of Transplantation, 5, 2253-2257, 2005.

Rayhill S, Kirby P, Voigt M, La Brecque D, Lutz C, Katz D, Mitros F, Kalil R, MillerR, Stolpen A, Heisey D, Wu Y, Schmidt W. Positive Cryoglobulin is associated with worse outcome after liver transplantation for chronic hepatitis C. Transplantation 80, 448-456, 2005.

Teaching:

• Lecturer for FCP course, Pharmacology courses, weekly conferences
• Faculty Series Director: Regular Scheduled Conferences: Nephrology/ Hypertension Research Conference, Category 1 CME
• Preceptor, Renal Physiology Seminar
• Mentor, American Physiological Society mentoring program for minority students
• Mentor for several post-doctoral researchers and physicians
• Judge, Internal Medicine Research Day (Graduate Student Posters)

Scholarship/Professional Productivity

• Areas of research interest:
• mechanisms involved in the activation of the mechanosensory nerve fibers in the renal pelvic wall
• Principal Investigator, funded by the NIH, VAMC, AHA
• Active collaborator with other investigators at the College of Medicine, as well as the Medical College of Georgia and the Karolinska Institute, Stockholm, Sweden

Clinical and Administrative Service

• Member, Editorial Board
  • American Journal of Physiology, Regulatory, Integrative and Comparative Physiology
  • American Journal of Physiology, Renal Physiology
• Reviewer for Journal of Clinical Investigation, American Journal of Physiology: Heart and Circulation Physiology, American Journal of Physiology: Renal Physiology, American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, American Journal of Physiology: Cellular and Molecular Physiology, Circulation, Journal of Neurochemistry, Hypertension, Brain Research, Journal of Physiology, Journal of Urology, Journal of The American Society of Nephrology, Kidney International, Acta Physiologica Scandinavica, Lipids
• Secretary/Treasurer, Iowa Physiological Society, 2002-2005

Recent Publications

Kopp, U.C., Cicha, MZ. And Smith, L.A. Differential Effects of Endothelin on the Activation of Renal Mechanosensory Nerves: Stimulatory in High and Inhibitory in Low Sodium diet. Am. J. Physiol. Epub.doi:10.1152/ajpregu.00878.2005

Kopp, U.C. and Zicha, M.Z. : Impaired Substance P Release from Renal Sensory Nerves in SHR Involves a Pertussis Toxin Sensitive Mechanism. Am. J. Physiol. 286 :R326-R333, 2004.

Kopp, U.C., Cicha, M.Z., Nakamura, K., Nusing, R.M., Smith, L.A. and H okfelt, T. Activation of EP4 Receptors Contributes to Prostaglandin E2 Mediated Stimulation of Renal Sensory Nerves. Am. J. Physiol. 287:F1269-F1282, 2004.

Alexandra Thomas, M.D.

Teaching

• Consistently rated as an excellent to outstanding teacher by students, residents, fellows and peers
• Director, Outpatient Internal Medicine Clerkship (2004-2006)
• Developed M4 electives that further take advantage of our Outpatient General Medicine Clinics
• Co-Director, “The Observer Speak: Medicine, Literature, and Writing” course
• Lecturer for FCPII and FCPIII course
• Preceptor for Professional and Personal Development in FCPI
• Clinician Mentor for FCPIV
• Participates quarterly in the Patient Based Assessment for the Ambulatory Practice Module
• Participated in panels and small groups on the Doctor and Self (Ambulatory Prac. Module)
• Educator of residents in Continuity of Care Clinics, Acute Care Clinic, and Internal Medicine services
• Lecturer, residents Ambulatory Curriculum
• Presented at various conferences at UIHC, as well as local, regional, and national meetings

Scholarship/Professional Productivity

• Areas of research interest:
• Develop longitudinal Internal Medicine Elective for senior medical students. First offered summer, 2004; curriculum for 2005-06 to reflect competencies for residency
• Participated in writing a $1.6 million grant for five years, awarded by the National Cancer Institute for teaching nutrition and cancer prevention to medical students
• Fellow, American College of Physicians
• Participate in the New Technologies in the Learning Environment workshop sponsored by University of Iowa Academic Technologies and received a $1500 “mini-grant” as part of this
• Author of textbook chapters on Skin Cancer and Menopause in First Exposure Internal Medicine, McGraw Hill, in press.

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Participant in the AAMC’s annual conference, Early Career Development of Women Faculty
• Participated in a panel discussion on “Career Paths for Women in Science and Engineering”
• Member, UIHC Child Care Center Parent Advisory Board
• Member, College of Medicine Promotions Committee
• Member, Neurology Review Ad Hoc Committee
• Member, Clinical Clerkship Task Force
• Member, Flock’s community faculty
• Mentor to medical students

Recent Publication

Snetselaar, L., Malville-Shipan, K., Ahrens, L., Smith, K., Chenard, C., Stumbo, P., Gordon, J., Thomas, A. Raising medical students' awareness of nutrition and fitness in disease prevention: nutrition and fitness program at the University of Iowa. Med Educ Online, 9:18, 2004.

To: Associate Professor of Clinical Medicine
Division: Pulmonary, Critical Care and Occupational Medicine

Medical School
Johns Hopkins University

Residency
Stanford University

Fellowship
The University of Iowa

Faculty Appointment
University of Iowa, 2001-