To: Associate Professor of Clinical Medicine
Division: Nephrology

Medical School:
UMDNJ-Robert Wood Johnson Medical School,
Piscataway, New Jersey

Residency:
Montefiore Medical Center (Chief Medical Resident)
Bronx, New York

Fellowship:
University of Pennsylvania

Faculty Appointment:
University of Iowa, 2000-

Teaching

• A gifted clinician educator and active contributor to all teaching programs from medical student to CME programs including Ambulatory Nephrology M3 Teaching Conferences; CBL lectures; FCP-I and FCP-IV small groups; Nephrology lectures in Human Organ Systems; weekly MKSAP review for residents and fellows
• Coordinated VA Lecture Series for primary care audiences
• Coordinated Core Conferences for medicine residents
• Participant, UI Teaching Scholars program
• Nominated, Housestaff Teacher of the Year, 2000
• Routinely rated as outstanding to excellent teacher by students, residents, fellows, and CME program participants
• Active mentor to medical students and residents

Scholarship/Professional Productivity

• Areas of research interest:
• evaluating script concordance testing
• nocturnal dialysis

Clinical and Administrative Service

• Active participant in all aspects of division clinical programs
  • Division coordinator for M3 Ambulatory Internal Medicine Clerkship

Recent Publications

Antes, L.M., Fernandez, P.C.: Principles of diuretic therapy. Disease-A-Month, 44 (6):254-68, 1998

Catella-Lawson, F., McAdam, B., Morrison, B.W., Kapoor, S., Kujubu, D., Antes, L., Lasseter, K.C., Quan, H., Gertz, B.J., Fitzgerald, G.A.: Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics and vasoactive eicosanoids. Journal of Pharmacology and Experimental Therapeutics, 289 ( 2):735-41, 1999.

Costanzo, E., Antes, L.M., Christensen A.J.: Behavorial and Medical Treatment of Chronic Polydipsia in a Patient with Schizophrenia and Diabetes Insipidus. Psychosomatic Medicine, 66(2):283-286, 2004.

To: Professor of Clinical Medicine
Division: Pulmonary, Critical Care and Occupational Medicine

Medical School:
Loyola Stritch School of Medicine
Chicago, Illinois

Residency:
University of Michigan

Fellowship:
The University of Iowa

Faculty Appointment:
The University of Iowa, 1992-

Teaching

• Consistently rated a very good to outstanding teacher by students, residents and fellows
• Contributor to FCP-IV, the UI Virtual Hospital, and an active lecturer on sleep disorders
• Educational Coordinator, UI Certified Sleep Fellowship Training Program
• Created and coordinates weekly Sleep Disorders Conference

Scholarship/Professional Productivity

• Areas of research interest:
• sleep disturbances of patients with complex medical disorders
• Active in development of divisional sleep curriculum and clinical program
• Invited speaker, including the annual meeting of American College of Chest Physicians (ACCP) and the Annual Meeting of the Associated Professional Sleep Societies
• Governor, Iowa Branch, ACCP

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Past member, UI Office of Consultation and Research in Medical Education Advisory Committee

Recent Publications

Strohl, K.P., Veasey, S., Harding, S., Skatrud, J., Berger, H.A., Papp, K., Dunagan, D., and Guilleminault, C.: Competency-based Goals for Sleep and Chronobiology in Undergraduate Medical Evaluation. Sleep, 26 (3): 333-36, 2003

Dyken, M.E., Yamada, T., and Berger, H.A.: Transient Obstructive Sleep Apnea and Asystole in Association with Presumed Viral Encephalopathy. Neurology, 60: 1692-1694, 2003

Dyken, M.E., Yamada, T., Glenn, C.L., and Berger, H. A.: Obstructive Sleep Apnea Associated with Cerebral Hypoxemia and Death. Neurology (an expedited and highlighted publication), 62: 491-493, 2004

To: Associate Professor of Clinical Medicine
Division: Cardiovascular Diseases

Medical School
Northwestern University

Residency
The University of Iowa

Fellowship
The University of Iowa

Faculty Appointment
The University of Iowa, 2000-

To: Associate Professor of Clinical Medicine
Division: General Internal Medicine

Medical School
University of Wisconsin

Residency
University of North Carolina

Faculty Appointment
The University of Iowa, 1994-

Teaching

• Curriculum Director, FCP-II for first-year medical students
• Member, Carver College of Medicine Curriculum Committee and Medical Education Committee
• Leadership role in curriculum development for medical students and residents
• Creator, Ambulatory Practice Module on Diabetes Mellitus for third-year medical students
• Active as medical student and resident preceptor
• Consistently rated as an excellent to outstanding teacher by students, residents, and fellows

Scholarship/Professional Productivity

• Areas of research interest:
• Patient education and monitoring behavior change
• Co-developed Family Care Center management for patients with Type 2 diabetes mellitus
• Group Leader, Delta Project Task Force for Diabetes (collaboration between UIHC and Wellmark)
• Active contributor to National Cancer Institute proposal on teaching nutritional aspects of cancer prevention to medical students
• Active contributor to curriculum design in multi-culturalism and women's health

Clinical and Administrative Service

• Active participant in all divisional clinical programs
• Clinical provider and liaison to the Meskwaki tribe to establish diabetes care and prevention programs
• Recognized as a preferred primary provider among UI employees
• Recipient, patient-initiated UIHC Above and Beyond Award
• Important contributor to creation of a primary care outreach clinic in Muscatine, Iowa

Teaching:

• Consistently rated an excellent to outstanding teacher by students, residents, fellows and CME program participants
• Developed monthly Molecular General Clinical Research Center Research conference and resident curriculum
• Active mentor for postdoctoral fellows and College of Public Health Ph.D. candidates
• Member, USMLE Ste 2 standard setting panel and on USMLE Step 3 test material development committee for acute care
• Frequently invited presenter at national and international meetings

Scholarship/Professional Productivity

• Areas of research interest:
• Modulation of inflammation in asthma using CpG oligonucleotides, helminths
• Control of airway remodeling in asthma
• Clinical studies of airway inflammation
• Mind-body interactions in asthma
• Asthma education
• Productive author with 18 papers since 2000
• Recipient, Outstanding Investigator Award, Central Society for Clinical Research, 2000
• Well funded research program
• Associate director, Environmental Health Sciences Research Center
• Associate director, General Clinical Research Center
• Ad hoc reviewer for the VA and NIAID
• Ad hoc journal reviewer
• Member, Asthma Working Group, Longitudinal Children's Study and planning committee of the Asthma, Allergy, and Immunology section of the American Thoracic Society
• Session chair, last five annual meetings of the American Thoracic Society

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Coordinator, Occupational Medicine Clinic
• Director, UI Adult Asthma Center
• Member of collegiate committees including the curriculum committee of graduate programs in immunology; GCRC advisory committee; and EHSRC advisory committee
• Member, Faculty Senate and Faculty Council
• Director, Midwestern Regional Pediatric Environmental Health Center

Recent Publications

Hussain, I., Jain, VV., O'Shaughnessy, P., Businga, T.R., Kline, J. Effect of Nitrogen Dioxide Exposure on Allergic Asthma in a Murine Model. Chest 126:198-204, 2004.

Jia, H.P., Kline, J.N., Penisten, A., Apicella, M.A., Gioannini, T.L., Weiss, J., McCray, P.B. Endotoxin Responsiveness of Human Airway Epithelia is Limited by Low Expression of MD-2. Am J Physiol Lung Cell Mol Physiol, 287:L428-437, 2004

Sigurdarson, S.T., O'Shaughnessy, P.T., Watt, J.A., Kline, J.N. Experimental Human Exposure to Inhaled Grain Dust and Ammonia: Towards A Model of Concentrated Animal Feeding Operations. Am J Ind Med, 46(4), 2004

Hussain, I., Kitagaki, K., Businga, T.R., Kline, J.N. Expression of Cysteinyl Leukotriene Receptor-1 in Skin. J Am Acad Dermatol, 51(6):1032-3, 2004

Durairaj, L., Launspach, J., Watt, J.L., Businga, T.R., Kline, J.N., Thorne, P.S., Zabner, J. Safety assessment of inhaled xylitol in mice and healthy volunteers. Respir Res. 2004 Sep 16 5(1): 13, 2004

Teaching

• Consistently rated an excellent to outstanding teacher by students, residents, fellows and CME program participants
• Active and enthusiastic participant at all levels of medical education including:
• medical students, residents, fellows
• post-doctoral students and graduate students in immunology and molecular biology, molecular physiology and biophysics, biological sciences, and epidemiology
• undergraduates in pharmacology, biomedical engineering
• MSTP summer enrichment program
• thesis review committees for the Departments of Physiology/Biophysics, Anatomy and Cell Biology, Biological Sciences, and the Graduate Programs in Immunology and Molecular Biology
• CME programs for community physicians
• Recipient of the Collegiate Teaching Award (2002); AOA Faculty Award (2003), M2 Teacher of the Year Award (2001, 2002)
• Regular participant in Office of Consultation and Research in Medical Education (OCRME) sponsored programs to improve his teaching effectiveness
• Successfully developed, implemented, and contributed to the improvement of educational programs including:
• co-directorship of the Medical Immunology course for M1 students
• membership on the program faculty for the "Mechanisms of Parasitism" NIH Training Grant
• coordination of Grand Rounds for the MSTP and the annual MSTP retreat
• participation in development of a course on Innate Immunity (in collaboration with Drs. Nauseef and Weiss)
• assistance in targeting educational programs for challenged and disadvantaged students
• membership on CCOM committees to enhance teaching and the evaluation of its effectiveness.

Scholarship/Professional Productivity

• Areas of research interest:
• signal transduction in innate immune cells, macrophage and dendritic cell function, tuberculosis, sepsis
• Internationally recognized investigator and speaker who has:
• presented at the FASEB Conference on "Phospholipase D" and at the American Society for Biochemistry and Molecular Biology, National Meeting
• co-chaired a symposium on "Phagocytosis" at the International Congress of Immunology (2004)
• presented at the 2005 Keystone Symposium on Tuberculosis

• Invited to author a chapter on Phospholipase D for Methods in Molecular Biology (Vol. 84, Transmembrane Signaling Protocols)
• Member, NIH study section
• Member, American Society of Clinical Investigation
• Ad hoc reviewer for several journals including Nature, The Journal of Biological Chemistry, The Journal of Clinical Investigation, Immunity, Journal of Infectious Diseases, and others
• Well funded research through the NIH and VA
• Steady productivity with papers appearing in high quality journals

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Member of several departmental, collegiate and University committees including:
  • Departmental Promotions Committees (2000, 2001)
  • VAMC Research and Development Committee
  • Enrichment Committee of the MSTP Program
  • University Biohazard Facility (PIII) Committee
  • Department of Internal Medicine Self Study Research Advisory Committee
  • Coordinated ID Research Conference
• Member, Bean Community in the CELLS medical student program
• Volunteer, Iowa City Free Medical Clinic and CPR instructor for Boy Scout and Cub Scout Organizations

Recent Publications

Thompson, C.R., Iyer, S.S., Melrose, N., VanOosten, R., Johnson, K., Pitson, S.M., Obeid, L.M., and Kusner, D.J. Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages. Inhibition of SK1 translocation by Mycobacterium tuberculosis . J. Immunol. 2005, 174:3551-3561

Kusner, D.J. Mechanisms of Mycobacterial Persistence in Tuberculosis. Clin. Immunol. 2005, 114:239-247

Iyer, S.S and Kusner, D.J. Assay of Phospholipase D activity in cell-free systems, in: Ali, H. and Haribabu, B.(Eds) Transmembrane Signalling Protocols, 2 nd Ed.  (Methods in Molecular Biology Vol. 84). Humana Press, Inc., Totowa, N.J. 2005 (in press)

Teaching:

• Consistently rated an excellent to outstanding teacher by students, residents, fellows and peers
• Very active teacher of medical students, physician assistant students, Internal Medicine residents, and Cardiology fellows at the bedside, in the Cardiology Clinic, and in the Echocardiography Laboratory

Scholarship/Professional Productivity

• Areas of research interest:
• clinical cardiovascular imaging, small animal imaging
• Active collaborator with investigators in the departments of Neurology and Pediatrics within the CLOSURE-1 trial

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs with a major role in staffing the Echocardiography Lab.
• Director, Cardiology Non-invasive Services
• Has played a vital role in the development of the nuclear cardiology imaging program in conjunction with the Department of Radiology
• Member, American Society of Nuclear Cardiology and American Society of Echocardiography

Recent Publications

Spencer, K.T., Lindower, P.D., Buettner, G.R., and Kerber, R.E.: Transition Metal Chelators Reduce Directly Measured Myocardial Free Radical Production During Reperfusion. J. Cardiovasc. Pharmacol., 32:343-348, 1998

Vandenberg, B.F., Zink, M.H., Ayers, R.W., Lindower, P.D., Rath, L.S., and Lewis, J.: Inhalation of Amyl Nitrite and the Measurement of Left Ventricular Outflow Velocity: Studies in Normal Young Adults. Echocardiography, 17:105-108, 2000

Vandenberg, B.F., Lindower, P.D., Lewis, J., and Burns, T.L. Reproducibility of Left Ventricular Measurements with Acoustic Quantification: The Influence of Training. Echocardiography, 17:631-637, 2000

James D. Rossen, M.D.

Teaching

• Consistently rated an excellent to outstanding teacher by students, residents, and fellows
• Very active participant in all levels of teaching including fellows in the Cardiac Catheterization Laboratory, and students, residents, and fellows in the outpatient Cardiology Clinic and in the CVICU on inpatient rotations.
• Recipient, Lewis E. January Clinical Teacher of the Year Award (2003)
• Director, Interventional Cardiology Fellowship Program

Scholarship/Professional Productivity

• Areas of research interest:
• anatomy and physiology of the human coronary circulation
• interventional cardiac catheterization
• Institutional co-principal investigator for the USVA COURAGE Trial
• Leader in acquisition of a magnetic stereotaxis laboratory, the first installed in Iowa
• Nationally recognized expert in the field of interventional cardiology:
• invited to present original research at national meetings, including the American Heart Association (AHA) Scientific Sessions
• Member, AHA Councils on Circulation and Clinical Cardiology

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs with a major role in staffing the Cardiac Catheterization Laboratory at UIHC and the Iowa City VAMC
• Director, UIHC Cardiac Catheterization Laboratory
• Director, Iowa City VAMC Cardiac Catheterization Laboratory
• Leader in the development of a combined vascular/medicine program with the division of vascular surgery

Recent Publications

A. Wahle, J.J. Lopez, E.C. Pennington, S.L. Meeks, K.C. Braddy, J.M. Fox, T.M.H. Brennan, J.M. Buatti, J.D. Rossen, and M. Sonka: "Effects of Vessel Geometry and Catheter Position on Dose Delivery in Intracoronary Brachytherapy." IEEE Transactions on Biomedical Engineering. 50(11):1286-95, 2003 Nov.

Shammas N.W., Pennell P., Rossen J.D., Winniford M.D., Carlisle T., Francis C.: "Evaluation of Fibrinolysis, Platelet Activation, and hemostatic Activation During High Dose Dobutamine Stress Echocardiography". International Journal of Angiology. 12:162-165, 2003

Wahle, A., Olszewski, M.E., Vigmostad, S.C., Medina, R., Coskun, A.U., Feldman, C.L., Stone, P.H., Braddy, K.C., Brennan, T.M.H., Rossen, J.D., Chandran, K.B., Sonka, M.: Quantitative Analysis of Circumferential Plaque Distribution in Human Coronary Arteries in Relation to Local Vessel Curvature. 2004 IEEE International Symposium on Biomedical Imaging, IEEE Press, pp. 531-534, 2004

To: Associate Professor of Clinical Medicine
Division: Infectious Diseases

Medical School
American University of Beirut

Residency
American University of Beirut
The University of Iowa

Fellowship
American University of Beirut
University of Iowa

Faculty Appointment
University of Iowa, 1994-

To: Associate Professor of Clinical Medicine
Division: Rheumatology

Medical School
University of Chicago

Graduate School (Immunology)
University of Chicago

Residency
The University of Iowa

Fellowship
The University of Iowa

Faculty Appointment
University of Iowa, 1997-

Teaching

• Consistently rated a good to excellent teacher by students, residents, fellows and peers
• Active participant at all levels in medical curriculum, including:
• clinical mentoring for M2s, M3 lectures, clinical teaching for M4s, and FCP IV lectures
• regular presentations to medical residents and physical therapy interns
• extensive fellows teaching in rheumatology clinic
• Highly sought speaker through the CCOM Visiting Professor Program and at regional meetings including the Lupus Foundation Meeting, Arthritis Foundation Patient Forum, and Iowa Dermatology Society

Scholarship/Professional Productivity

• Areas of research interest:
• Supervisor for several Rheumatology Fellow research projects, including relationship between fatigue and vitamin D deficiency in patients with systemic lupus.
• Author, review on use of DMARDS in rheumatoid arthritis (2002); sections on osteoarthritis and scleroderma for the Rheumatic Diseases Chapter of Turek's Orthopaedics (2005); chapter on immune effect of bacterial DNA in Lupus: Molecular and Cellular Pathogenesis (1999)

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs with a major role in patient care in the teaching setting.
• Assistant Director, Rheumatology Clinical Programs
  • coordinates faculty clinic schedules
  • leader in developing communications between clinic personnel, staff, and faculty
  • coordinates VA rheumatology clinics
  • designed and implemented pre-appointment management system
  • implemented injection clinic

Recent Publications

Yi, A.-K., Tuetken, R., Redford, T., Waldschmidt, M., Kirsch J. and Krieg, A.M.: CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species. J Immunol., 160(10):4755-61, 1998.

Tuetken, R., Yi, A-K., and Krieg, A.M.. 1999. The immune effects of bacterial DNA and their possible role in the pathogenesis of lupus. In: Tsokos,G., and Kammer, G. 1999 Lupus: Molecular and Cellular Pathogenesis, vol. 7 pages 79-100 of Contemporary Immunology (The Humana Press: Totowana N.J. ) 1999

Schrand, L.M. and Tuetken, R. Rheumatoid arthritis: Update on the newest DMARDs and their place in therapy. Formulary 2002; 37(6): 301-311.

To: Professor of Medicine
Division: Cardiology

Medical School
Tulane University

Residency
Emory University
University of Illinois

Fellowship
St. Louis University

Faculty Appointment
University of Illinois, 1987-1995
University of Iowa, 1995-

Teaching

• Consistently rated an excellent to outstanding teacher by students, residents, fellows and peers
• Active mentor for residents, clinical fellows, and graduate and post-graduate students
• Former Co-director, MSTP Summer Program

Scholarship/Professional Productivity

• Areas of research interest:
• understanding the role of lipid mediators, oxidative stress and inflammation in vascular biology
• Very productive author whose work appears in high quality journals including Circulation Research, the Journal of Immunology and Journal of Biological Chemistry.
• Active collaborator with other investigators
• Excellent research funding through the NIH
• Member, editorial boards of the American Journal of Physiology: Heart and Circulatory Physiology and Arteriosclerosis, Thrombosis and Vascular Biology

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs with a major role in institutional management
• Interim director, Division of Cardiology
• Director, UI Heart Center

Recent Publications

Fang, X., Hu, S., Watanabe, T., Weintraub, N.L., Snyder, G.D., Yao, J., Liu, Y., Shyy, J. Y-L., Hammock, B.D., and Spector, A.A.: Activation of Peroxisomal Proliferator-activated Receptor- a by Substituted Urea-derived Soluble Epoxide Hydrolase Inhibitors. J Pharmacol Exp Ther ., (in press) 2005

Kabra R., Welke K.F., Kernstine K.H., Field F.J., Thompson B.H., Vats H.S., and Weintraub N.L. Bacterial Pericarditis Due to Group F Streptococcus as a Complication of Esophagomediastinal Fistula. Ann. Thoracic Surg., 79(6):2132-2134, 2005.

Gavrila, D., Li, W.-G., Daugherty, A., Cassis, L.A., Miller, F.J. Jr,, Oberley, L.W., Dellsperger, K.C., and Weintraub, N.L. Vitamin E Inhibits Abdominal Aortic Aneurysms Formation in Angiotensin II-infused, ApolipoproteinE-deficient Mice. Arterioscler. Thromb. Vasc. Biol ., In Press, 2005

Teaching

• Consistently rated an excellent to outstanding teacher by students, residents, fellows and peers
• Member, Immunology Graduate Program
• Member, Medical Science Training Program
• Active mentor for graduate students, medical students and undergraduates
• Active participant in Division of Allergy & Immunology fellowship training program and in Applied Immunology Curriculum for medicine fellows.
• Co-chair, monthly Interdisciplinary Seminar in Transplantation Medicine

Scholarship/Professional Productivity

• Areas of research interest:
• Immunology and stem cell biology
• Productive author with publications in high quality peer-reviewed journals
• Successful funding through the VA, NIH, AHA and ROTR (Transplant Research Foundation)
• Member, NIH and International Grant review panels
• Invited speaker at national and international conferences

Clinical and Administrative Service

• Active participant in all aspects of divisional clinical programs
• Director, Transplantation Research, Division of Allergy & Immunology
• Associate Director, Iowa City VA Tissue Typing Laboratory
• Chair, UI Advisory Committee on Stem Cell Research
• Member, Student Advisory Group on Diversity

Recent Publications

Chandraker, A., Huurman, V., Hallett, K., Yuan, X., Tector, A.J., Park, C.H., Lu, E., Zavazava, N., and Oaks, M.: CTLA-4 is Important in Maintaining Long-Term Survival of Cardiac Allografts. Transplantation 79 :897-903, 2005

Fabricius, D., Bonde, S., and Zavazava, N.: Induction of Stable Mixed Chimerism by Embryonic Stem Cells Requires Functional Fas/FasL Engagement. Transplantation 79 :1040-1044, 2005

Fried, A., Berg, M., Sharma, B., Bonde, S. and Zavazava, N. Recombinant dimeric MHC antigens protect cardiac allografts from rejection and visualize alloreactive T cells. J. Leukoc. Biol. 2005 Jul 6; [Epub ahead of print]