Department of Internal Medicine

Rheumatology Faculty

Petar Lenert photo

Medical School:
University of Novi Sad,
Yugoslavia

Graduate School:
University of Belgrade,
Yugoslavia, 1981 (M.Sc.) 
University of Novi Sad,
Yugoslavia, 1991 (Ph.D.)

Residency and Fellowship:
University of Novi Sad,
Yugoslavia

Post Graduate Training:
University of California,  San Diego
University of Montreal, Quebec
The University of Iowa

Petar Lenert, M.D., M.Sc, Ph.D.
Assistant Professor

Dr. Lenert is interested in the study of the mechanisms of CpG-induced receptor binding and downstream signal transduction evens in human and mouse B cells.  His clinical interest is in the area of systemic autoimmune diseases.

Recent Publications

  1. Lenert, P., Goeken, A., Handwerger, B. and Ashman, R.F.: Innate immune responses in lupus-prone Palmerston North mice: Differential responses to LPS and bacterial-DNA/CpG-oligonucleotides. J. Clin. Immunol. 23: 202-213 (2003).
  2. Lenert, P., Yi, A-K., Krieg, A.M., Stunz, L.L and Ashman, R.F.: Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells. Antisense Nucleic Acid Drug Dev. 13:143-150 (2003).
  3. Lenert, P., Rasmussen, W., Ashman, R.F., and Ballas, Z.K. Structural chraracterization of the inhibitory DNA motif for the type A(D)-CpG-induced cytokine secretion and NK-cell lytic activity in mouse spleen cells. DNA Cell. Biol. 22: 621-631 (2003).
  4. Stunz, L.L., Lenert, P., Peckham, D., Yi, A-K., Haxhinasto, S., Chang, M., Krieg, A.M. and Ashman, R.F.: Inhibitory CpG oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells . Eur J Immunol 32:1212-1222, 2002.
  5. Chen, Y., Lenert, P., Weeratna, R., McCluskie, M., Wu, T., Davis, H.L. and Krieg, A.M.: Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs. Gene Ther 8: 1024-1032, 2001.
  6.   Lenert, P., Stunz, L., Yi, A-E., Krieg, A.M. and Ashman, R.F.: CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kB activation. Antisense Nucleic Acid Drug Dev 11: 247-256, 2001.

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