Department of Internal Medicine
Pulmonary, Critical Care and
Occupational Medicine Faculty
Rama K. Mallampalli, M.D.
Professor
Dr. Mallampalli's clinical interests are in general pulmonary medicine, immune alveolar hemorrhage syndromes, and in clinical outreach services. His research interests are in area of the acute respiratory distress syndrome, focusing on the regulation of surfactant phospholipid production.
Honors, Awards, and Organizations
- Diplomate, American Board of Internal Medicine and Board of Pulmonary Diseases
- Diplomate, Board of Critical Care Medicine
- American College of Chest Physicians, Fellow
- American Thoracic Society
- Society for Pediatric Research
- American Society for Biochemistry and Molecular Biology
- Clinical Investigator Award, NIH/NICHD
- Clinician Scientist Award, American Heart Association
- FIRST Award, NIH/NHLBI
- Established Investigator, American Heart Association
- Merit Review Award, Veteran's Administration
- Career Investigator, American Lung Association
- American Society of Clinical Investigation (ASCI)
- Editorial Board, The Journal of Biological Chemistry
- Charter Member, NIH /CSR Lung Injury, Remodeling, and Repair Study Section
|
Medical School:
University of Wisconsin
Residency:
Hennepin County Medical Center
Fellowship:
The University of Iowa |
Recent Publications
- Ryan, A.J., Andrews M., Zhang L., Zhou J., and Mallampalli, R.K. c-Jun N-terminal kinase regulates CTP:phosphocholine cytidylyltransferase., Arch. Biochem. Biophys. 447:23-33, 2006.
- Zhou J., Wu, Y., Henderson, F., McCoy, D.M., Salome, R.G., McGowan, S.E., and Mallampalli, R.K. Adenoviral gene transfer of a mutant surfactant enzyme ameliorates pseudomonas-induced lung injury. Gene Ther. 13:974-985, 2006.
- McCoy, D.M, Fisher K., Robichaud J., Ryan, A.J., and Mallampalli, R.K. Transcriptional regulation of lung cytidylyltransferase in developing transgenic mice. Am. J. Respir. Cell Mol. Biol 35: 394-402, 2006.
- Henderson, F., Miakotina, O.L., and Mallampalli, R.K. Proapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesis. J. Lipid Res. 47:2314-2324, 2006.
- Wu,Y., Xu, Z., Henderson, F.C., Ryan, A.J., Yahr, T,L. and Mallampalli, R.K. Chronic P. aeruginosa infection reduces surfactant levels by inhibiting its biosynthesis. Cell. Microbiol. 4:1062-1072, 2007.
- Agassandian M., Miakotina, O.L., Andrews, M., and Mallampalli, R.K. P. aeruginosa and sPLA2 stimulate ABCA1-mediated phospholipid efflux via ERK-activation of PPARα/RXR. Biochem. J. 403:409-420, 2007.
- Miakotina, O.L., Ryan, A.J., Salome, R.G., McCoy, D.M., Look, D.C., and Mallampalli, R.K. Human adenovirus modulates surfactant phospholipid trafficking. Traffic. (In Press), 2007.
- Chen, B.B. and Mallampalli, R.K. Calmodulin binds and stabilizes the regulatory enzyme, CTP:phosphocholine cytidylyltransferase. J. Biol. Chem. (In Press), 2007.
Links of Interest
Back to Pulmonary Faculty List |
