Department of Internal Medicine
Pulmonary, Critical Care and
Occupational Medicine Faculty
Medical School:
Duke University
Residency:
University of Washington
University of Colorado
Fellowship:
University of Colorado
D. Michael Shasby, M.D.
Professor
Dr. Shasby's research examines the acute inflammatory response and how it affects lung endothelial and epithelial surfaces. His current work focuses on cell adhesion molecules and how their function is altered by inflammatory agonists such as histamine. His clinical interests are in critical care, bronchoscopy and asthma.
Honors, Awards, and Organizations
- Alpha Omega Alpha
- Diplomate, American Board of Internal Medicine, Pulmonary Diseases, and Critical Care Medicine
- American College of Chest Physicians
- American College of Physicians, Member
- American Heart Association Established Investigator Award
- American Society for Clinical Investigation
- American Thoracic Society
- Central Society for Clinical Research
- Veterans Administration, Clinical Investigator
- Phi Beta Kappa
- Association of American Physicians
Recent Publications
- Michael C. Winter, Sandra S. Shasby, Dana R. Ries, and D. Michael Shasby. Histamine selectively interrupts VE-cadherin adhesion independent of capacitive calcium entry. Am J Physiol Lung Cell Mol Physiol (in press).
- Joseph Zabner, Michael Winter, Katherine J.D. Ashbourne Excoffon, David Stoltz, Dana Ries, Sandra Shasby, and Michael Shasby. Histamine alters E-cadherin cell adhesion to increase human airways epithelial permeability. J Appl Physiol. 95:394-401, 2003.
- Shasby DM, Ries DR, Shasby SS, Winter MC. Histamine stimulates phosphorylation of adherens junction proteins and alters their link to vimentin. Am J Physiol (Lung) 282:L1330-L1338, 2002.
Links of Interest