Department of Internal Medicine

Pulmonary, Critical Care and
Occupational Medicine Faculty

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Gary W. Hunninghake, M.D.
Sterba Professor of Medicine
Director, UI Institute for Clinical and Translational Science

Dr. Hunninghake's clinical and research interested include the areas of sarcoidosis, asthma, occupational lung disease, and interstitial lung disease. Dr. Hunninghake's basic studies emphasize molecular and cellular biology, virology and second messenger studies.

Dr. Hunninghake is also the Director of the Graduate Program in Translational Biomedical Research and the Director of the Training Program in Molecular and Cellular Biology of the Lung (NHLBI)

Links of Interest

• UI Institute for Clinical and Translational Science
• Community of Science Profile

Honors, Awards, and Organizations

• Alpha Omega Alpha
• American Academy of Allergy
• American Association of Immunologists
• American Association of Physicians
• Diplomate, American Board of Internal Medicine
  • Board of Pulmonary Diseases
  • Board of Allergy and Immunology
  • Board of Critical Care Medicine
• American College of Chest Physicians
• American College of Physicians
• American Federation for Clinical Research 
  • National Councilor, 1982
  • President, 1986
• American Society for Clinical Investigation
• American Thoracic Society
  • Secretary-Treasurer, 1991-93
  • Vice President, 1992-93
  • President, 1993-94
• Association of American Physicians
• Central Society for Clinical Research
  • President, 1997-1998
• Fleischner Society
• AAIM-Merck Executive Leadership Program, 2004
• J. Burns Amberson Lecture, American Thoracic Society, 2006
• University of Iowa Carver College of Medicine Distinguished Mentor Award, 2007
• Member, The American Clinical and Climatological Association, 2008
• Murray Kornfeld Memorial Founders Lecture, American College of Chest Physicians, 2008

Faculty Positions:

• Laboratory of Clinical Investigation, National Institute for Allergy and Infectious Diseases, NIH, 1974-77
• Consultant, Bethesda Naval Hospital, Bethesda, Mayland, 1974-77
• Pulmonary Branch, National Heart, Lung, and Blood Institute, NIH, 1977-81
• The University of Iowa College of Medicine, 1981-

Recent Publications

1. Hansdottir, S., Monick M.M., Hinde, S.L, Lovan, N., Look, D.C. and Hunninghake, G.W.  Respiratory Epithelial Cells Convert Inactive Vitamin D to its Active Form: Potential Effects on Host Defense.  J Immunol.  181:7090-7099, 2008. 
2. Monick, M.M., Powers, L.S., Barrett, C., Hinde, S., Ashare, A., Groskreutz, D., Nyunoya, T., Coleman, M., Spitz, D.R. and Hunninghake, G.W.  Constitutive ERK MAP activity regulates macrophage ATP production and mitochondrial integrity.  J Immunol.  180:7485-7496, 2008.
3. Groskreutz, D.J., Monick, M.M., Yarovinsky, T.O., Powers, L.S., Quelle, D.E., Varga, S.M., Look, D.C., and Hunninghake, G.W.  Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells.  J Immunol.  179(5): 2741-2747, 2007.
4. Monick, M.M., Powers, L.S., Hassan, I., Groskreutz, D., Yarovinsky, T.O., Barrett, C.W., Castilow, E.M., Tifrea, D., Varga, S.M., and Hunninghake, G.W.  Respiratory syncytial virus synergizes with Th2 cytokines to induce optimal levels of TARC/CCL17.  J Immunol.  179(3):1648-58, 2007.
5. Gross, T.J., and Hunninghake, G.W.: Idiopathic Pulmonary Fibrosis. N. Engl. J. Med., 345(7):517-525, 2001.
6. Hunninghake, G.W., Costabol, U., Ando, M., Baughman, R., Cordier, J.F., du Bois, R., Ecklund, A., Kitaichi, M., Lynch, Jl, Rizzato, G., Rose, C., Selroos, O., Semenzato, G., and Sharma, O.P. ATS/ERS/WASOG Statement on Sarcoidosis. Am. J. Respir. Crit. Care Med. 160:736-755, Eur Respir J. 14:735-737, Sarcoidosis Vasc. Diffuse Lung Dis. 16:149-173, 1999.

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