Christie P. Thomas, M.D.
Professor
The research in Dr. Thomas' lab is focused on the regulation of the amiloride-sensitive epithelial sodium channel. This channel is expressed in the distal nephron, the lung and the colon. This channel mediates aldosterone responsive sodium reabsorption in the collecting ducts and is mutated in certain forms of genetic hypertension and in salt-wasting syndromes. Dr. Thomas has defined the molecular structure of the human channel subunit genes. He is evaluating the mechanisms that regulate expression of these gene products, focusing on aldosterone and glucocorticoids, two hormones that are potent activators of gene expression and sodium reabsorption in the terminal nephron. His work is supported by the NIH and the VA. He is a faculty member in the Molecular and Cellular Biology Granduate Program.
Dr. Thomas' clinical interests are in renal transplantation and in genetic disorders of the kidney. He directs the Kidney Transplant Program at the VA Medical Center. He is also the director of the Iowa Medical Student Research Program.
Honors, Awards, and Organizations
- Diplomate, American Board of Internal Medicine & Subspecialty Board in Nephrology
- American College of Physicians, Fellow
- American Heart Association
- Council on Kidney in Cardiovascular Diseases, Member
- Council on Hypertension, Fellow
- Established Investigator, 2000-2004
- American Lung Association, Career Investigator, 2000-2003
- Royal College of Physicians, UK, Fellow
- National Kidney Foundation, Young Investigator, 1993-1995
- American Society of Nephrology, Fellow
- Member, Medical Advisory Board, National Kidney Foundation of Iowa
- Member, AST Organ Donation Committee
- Board of Directors, Iowa Donor Network
- Member, UNOS Organ Availability Committee
- Volunteer, Iowa City Free Medical Clinic
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Medical School:
University of Madras at Christian Medical College, Vellore, India
Residency:
District General Hospital, Sunderland, UK
Royal Hallamshire and Northern General Hospitals, University of Sheffield, UK
Fellowship:
Case Western Reserve University |
