Department of Internal Medicine
Elizabeth Hirak Field, M.D.
Dr. Field's research interest is immunologic tolerance in transplantation and autoimmunity. The laboratory specifically examines the mechanisms of immunoregulatory networks in acquired tolerance and is characterizing the cellular and molecular pathways by which CD4+CD25+ regulatory cells induce or maintain acquired tolerance to foreign MHC antigens.
Honors, Awards, and Organizations
- American Board of Internal Medicine, Diplomate
- American Association of Immunologists
- American College of Physicians, Associate
- American College of Rheumatology
- American Society for Clinical Investigation
- American Society for Histocompatibility and Immunogenetics
- American Society of Transplantation (formerly ASTP)
- Central Society for Clinical Research
- Clinical Immunology Society
- Transplantation Society
- Pennsylvania State University College of Medicine Alumni Award, 1998
- Central Society for Clinical Research, Outstanding Young Investigator, 1997
- VA Medical Research Advisory Group, Immune Disorders
- Gao, Q., Rouse, T., Kazmerzak, K., and Field, E.H.: CD4+CD25+ Cells Regulate CD8 T Cell Anergy in Neonatal Tolerant Mice. Transplantation 68:1891-1897, 1999.
- Field, E.H., and Strober, S.: Tolerance, Mixed chimerism, and protection against graft versus host disease after total lymphoid irradiation (TLI). Philosophical Transactions of the Royal Society 2001 May;356(I409):739-48.
- Field, E.H., Matesic, D., Rigby, S., Fehr, T., Rouse, T., and Gao, Q.: CD4+CD25+ Regulatory cells in acquired MHC tolerance. Immunological Reviews, 182:99-112, 2001.
- Field, E.H. and Rouse, T.: Requirements for developing mixed-chimerism in non-myeloablative total lymphoid irradiated mice: Role of IL-4 and immunoredirection. Transplantation (in press) 2002.