Department of Internal Medicine

Infectious Diseases Faculty

Additional Publications

1. Stapleton JT, Klinzman D, Schmidt WN, Pfaller MA, Wu P, LaBrecque DR, Han J-Q, Perino-Phillips MJ, Woolson R, Alden B.  Prospective Comparison of Whole Blood- and Plasma-Based Hepatitis C Virus RNA Detection Systems:  Improved Detection Using Whole Blood as the Source of Viral RNA.  J. Clin. Micro.  37:484-489, 1999.
2. Cederna, JB, Klinzman D, Stapleton, JT.  Hepatitis A virus-specific humoral and cellular immune responses following immunization with a formalin-inactivated hepatitis A vaccine.  Vaccine,  18:892-898, 2000.
3. Schmidt WN, Stapleton JT, LaBrecque DR, Mitros FA, Kirby PA, Phillips MJ, Brashear DL.  Hepatitis C virus (HCV) infection and cryoglobulinemia:  Analysis of whole blood and plasma HCV-RNA concentrations and correlation with liver histology.  Hepatology  31:737-744, 2000.
4. Wünschmann S and Stapleton JT.  Fluorescence-based quantitative methods for detecting Human Immunodeficiency Virus Type 1-induced syncytia.  J Clin Micro.  38:3055-3060, 2000.
5. Xiang J, Wünschmann S, Schmidt WN, Shao J, Stapleton JT. Full-length GB virus C (Hepatitis G Virus) RNA transcripts are infectious in primary CD4 positive T cells.  J. Virol. 74:9125-9133,  2000.
6. Wünschmann S, Medh J, Klinzman D, Schmidt WN, Stapleton JT.  Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low density lipoprotein receptor.  J. Virol. 74:10055-10062,  2000.
7. Vargas K, Messer SA, Pfaller M, Lockhart S, Stapleton JT, Hellstein J, Soll DR.  Elevated switching and drug resistance of Candida from HIV-Positive individuals prior to thrush.  J. Clin. Micro.  38:3595-3607,  2000.
8. Xiang J, Wuenschmann S, Diekema D, Klinzman DJ, Patrick KD, George SL, Stapleton JT.  Effect of CoInfection with GB Virus C on Survival Among Patients with HIV Infection.  N.Engl.J.Med. 345:707-714, 2001.
9. Schmidt WN, Stapleton JT.  Whole-Blood Hepatitis C Virus RNA Extraction Methods.  J. Clin. Micro.  39:3812, 2001.
10. Stapleton JT, Diekema DJ, Xiang J.  GB virus C and mortality from HIV infection.  (letter) N.Engl.J.Med. 346:378.  2002.
11. Kresina TF, Flexner CW, Sinclair J, Correia MA, Stapleton JT, Adeniyi-Jones S, Cargill V, Cheever LW.  Alcohol Use and HIV Pharmacotherapy.  AIDS Res. Hum. Retro.  18:757-770, 2002.
12. Xiang J, Wünschmann S, Schmidt WN, George S, Schmidt WN, LaBrecque DR, Stapleton JT.  Recombinant hepatitis C virus-like particles expressed by baculovirus:  Utility in cell-binding and antibody detection assays.  J.Med.Virol.  68:537-543,  2002.
13. George SL, Gephardt J, Klinzman D, Foster MB, Patrick KD, Schmidt WN, Alden B, Pfaller MA, Stapleton JT.  Hepatitis C virus (HCV) viremia in HIV-infected individuals with negative HCV antibody tests.  J. Acquir. Immune Defic. Syndr.  31:154-162, 2002.
14. Stapleton JT.  Hepatic and Pancreatic Diseases in HIV Infection.  In:  Approach Towards Management of Human Immunodeficiency Virus Infection and Its Related Complications.  Singh N, Shafer RW, and Swindells S, eds., ESUN Technologies, Pittsburgh.  Online Text at:  www.antimicrobe.org. 2003.  Condensed chapter in HIV Clinical Manual, pp. 181 – 213, 2003.
15. Stapleton JT.  GB Virus type C/Hepatitis G Virus.  Seminars in Liver Disease.  23:137-148.  2003.
16. Polgreen PM, Putz D, Stapleton JT.  Inaccurate glycosylated hemoglobin A1C measurements in HIV-positive patients with diabetes mellitus.  Clin Infect. Dis. 37:e53-56, 2003.
17. Polgreen P, Xiang J, Stapleton JT.  GB Virus C – HIV Co-Infection.  Microbes and Infection.  5:1255-1261, 2003.
18. George S, Xiang J, Stapleton JT.  Clinical isolates of GB virus type C vary in their ability to persist and replicate in peripheral blood mononuclear cell cultures.  Virology.  316:191-201, 2003.
19. Kim SJ, Jang MH, Stapleton JT, Yoon SO, Jeon ES, and Hong HJ.  Neutralizing Human Monoclonal Antibodies to Hepatitis A Virus Recovered by Phage Display.  Virology.  318:598-607, 2004.
20. Stapleton JT, Williams CF, Xiang J.  GB Virus C:  A beneficial infection?  J.Clin.Micro.  42:3915-3919,  2004.
21. Polgreen PM, Fultz SL, Justice AC, Wagner JH, Diekema DJ, Rabeneck L, Weissman S, Stapleton JT.  Association of Hypocholesterolemia With Hepatitis C Virus Infection in HIV Infected People.  HIV Med. 5:144-150, 2004.
22. Ullrich PM, Lutgendorf SK, Stapleton JT, Horowitz M.  Self Regard and Concealment of Homosexuality as Predictors of CD4+ Cell Count Over Time Among HIV Seropositive Gay Men.  Psychology & Health.  19:183-196, 2004.
23. Weintraub A, Hamilton JD, Hahn C, Klinzman D, Moyo G, Zdunek D, Hess G, Benjamin DK, Stapleton JT.  Active or Prior GB Virus C Infection Does Not Protect Against Vertical Transmission of HIV in Co-Infected Women from Tanzania.  Clin. Infect. Dis. 38:e46-48, 2004.
24. Stapleton JT, Williams CF, Xiang J.  GB virus C and HIV interactions.  N.Engl.J.Med., 350:2618,2004, 2004.
25. Stapleton JT, Chaloner K.  GB Virus C and survival in HIV-positive people.  AIDS.  18:2343-2344, 2004.
26. Talbot TR, Stapleton JT, Brady RC, Winokur PL, Bernsteing DI, Germanson T, Yoder SM, Rock MT, Crowe JR. JE, Edwards KM.  Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine:  A randomized controlled trial.  JAMA 292:1205-1212,  2004.
27. Stapleton JT, Chaloner K, Williams CF.  GB virus C and survival in the Amsterdam Cohort Study.  J Infect Dis.  191:2157-2158.  2005.
28. Schuval S, Lindsey JC, Stapleton JT, Van Dyke RB, Palumbo P, Mofenson LM, Oleske JM, Cervia J, Kovacs A, Dankner WN, Smith E, Nowak B, Ciupak G, Webb N, Eagle M, Smith D, Hennessey R, Goodman-Kerkau M, Klinzman D, Hess G, Zdunek D, Levin MJ; the Pediatric AIDS Clinical Trials Group Protocol 1028S Team.  GB Virus C Infection in Children With Perinatal Human Immunodeficiency Virus Infection.  Pediatr Infect Dis J.  24:417-422, 2005.
29. Bisson G, Strom B, Gross R, Weissman D, Klinzman D, Hwang W-T, Kostman J, Hess G, Zdunek D, Metzger D, Stapleton JT, Frank I.  Effect of GB virus C viremia on HIV acquisition and HIV set-point.  AIDS.  19:1910-1912, 2005.
30. Xiang J, Sathar MA, McLinden J, Klinzman D, Chang Q, Stapleton JT.  South African GB virus C isolates:  Interactions between genotypes 1 and 5 GBV-C isolates and the human immunodeficiency virus.  J. Infect. Dis.  192:2147-2151, 2005.
31. Souza IE, Zhang W, Diaz RS, Chaloner K, Klinzman D, Stapleton JT.  Effect of GB Virus C on response to antiretroviral therapy in HIV infected Brazilians.  HIV Med 7:25-31, 2006.
32. Zhang W, Chaloner K, Tillmann HL, Williams CF, Stapleton JT.  Effect of early and late GBV-C viremia on survival of HIV infected individuals: a meta-analysis.  HIV Med, 7:173-180, 2006.
33. George SL, Varmaz D, Stapleton JT.  GB virus C replicates in primary T and B lymphocytes.  J. Infect. Dis.  193:451-454, 2006.
34. Souza IE, Allen JB, Xiang J, Klinzman D, Diaz R, Zhang S, Chaloner K, Zdunek D, Hess G, Williams CF, Benning L, Stapleton JT.  Optimal testing for GB Virus C viremia:  Effect of primer selection on estimates of GBV-C prevalence and response to antiretroviral therapy.  J. Clin. Microbiol. 44:3105-3113, 2006.
35. Wünschmann S, Müller HM, Stipp CS, Hemler ME, Stapleton JT.  In Vitro interaction between hepatitis C virus (HCV) envelope glycoprotein E2 and serum lipoproteins (LPs) results in enhanced cellular binding of both HCV E2 and LPs.  J. Infect. Dis.  194:1058-1067,  2006.
36. Kayali Z, Tan S, Shinkunas L, Voigt M, LaBrecque DR, Stapleton JT, Brown KE, Schmidt WN.  Risk Factors for Hepatitis C Fibrosis:  A Prospective study of United States Veterans compared to Non-veterans.  J Viral Hep, 14:11-21, 2007.
37. Couch RB, Winokur P, Edwards KM, Black S, Atmar RL, Stapleton JT, Kissner JM, Shinefield H, Denny TM, Michael J. Bybel, Newman FK, Yan L.  Reducing the Dose of Smallpox Vaccine Reduces Vaccine-Associated Morbidity Without Reducing Vaccination Success Rates or Immune Responses.  J Infect Dis.  195:826-832, 2007.
38. Dillon DMB, Stapleton JT.  Selenium effects on HIV RNA and CD4 Cell Counts.  Arch Intern Med.  167:1556-1557 2007.
39. Scherer CA, Magness CL, Steiger KV, Poitinger ND, Caputo CM, Miner DG, Winokur PL, Klinzman D, McKee J, Pilar C, Ward PA, Gillham MH, Haulman NJ, Stapleton JT, Iadonato SP.  Distinct Gene Expression Profiles in Peripheral Blood Mononuclear Cells from Patients Infected with Vaccinia Virus, Yellow Fever 17D Virus, or Community Acquired Upper Respiratory Infections.  Vaccine 25:6458-73, 2007.
40. Chang Q, McLinden JH, Stapleton JT, Sathar AM, Xiang J.  GB Virus C NS5A protein from genotypes 1, 2, 3, and 5 and a 30 amino acid NS5A fragment expression inhibit HIV-1 replication in a CD4+ T-lymphocytes.  J Gen Virol  88:3341-3346, 2007.
41. Stapleton JT, Bennett K, Bosch RJ, Polgreen PM, Swindells S.  Effect of antiretroviral therapy and hepatitis C coinfection on changes in lipid levels in HIV-infected patients 48 weeks after initiation of therapy.  HIV Clin Trials, 8:429-436, 2007.
42. Zhang W, Chaloner K, Cowles MK, Zhang Y, Stapleton JT.  A Bayesian analysis of doubly censored data using a hierarchical Cox model.  Statist. Med.  In Press.  2007.

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