Department of Internal Medicine

Hematology, Oncology and Blood &
Marrow Transplantation Faculty

George J. Weiner, M.D.

Additional Publications

Jahrsdorfer, B, Mühlenhoff, L, Blackwell, SE, Wagner, M, Poeck, H, Hartmann, E, Jox, R, Giese, T, Emmerich, B, Endres, S, Weiner, GJ, and Hartmann, G. B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides. Clinical Cancer Research, 11:1490-1499, 2005.
Jahrsdörfer, B, Wooldridge, JE, Blackwell, SE, Taylor, CM, Griffith, TS, Link, BK, and Weiner, GJ. Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells. J. Leukocyte Biology, 77: 378-387, 2005.
Jahrsdörfer, B, Blackwell, SE, and Weiner, GJ. Phosphorothyoate oligodeoxynucleotides block nonspecific binding of Cy5 conjugates to monocytes. J. Immunological Methods, 297: 259-263, 2005.
Weiner, GJ, and Link, BK. Antibody Therapy of Lymphoma. Advances in Pharmacology, Vol 51: 229-253, 2004.
Bevaart, L, Van Ojik, HH, Sun, AW, Sulahian, TH, Leusen, JH, Weiner, GJ, Van De Winkel, JG, Van Vugt, MJ. CpG oligodeoxynucleotides enhance FcgammaRI-mediated cross presentation by dendritic cells. Int Immunol 16, 1091-8, 2004.
Baral, RN, Saha, A, Chatterjee, SA, Foon, KA, Krieg, AA, Weiner, GJ, and Bhattacharya-Chatterjee, M. Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigen. Cancer Immunol Immunother, 52:317, 2003.
Bains, SK, Mone, A, Tso, JY, Lucas, D, Byrd, JC, Weiner, GJ, and Green, JM. Mitochondria control of cell death induced by anti-HLA-DR antibodies. Leukemia, 17:1357, 2003.
Jahrsdoerfer, B, and Weiner, GJ. Immunostimulatory CpG Oligodeoxynucleotides and Antibody Therapy of Cancer. Seminars in Oncology, Vol 30, No 4 (August): 476-482, 2003.
van Ojik HH, Bevaart L, Dahle CE, Bakker A, Jansen MJH, van Vugt MJ, van de winkel JGJ, and Weiner GJ. CpG-A and B oligodeoxynucleotides Enhance the Efficacy of Antibody Therapy by Activating Different Effector Cell Populations. Cancer Research, 63: 5595-5600, 2003.
Feldman, E., Kalaycio, M., Weiner, G., Frankel, S., Schulman, P., Schwartzberg, L., Jurcic, J., Velez-Garcia, E., Seiter, K., Scheinberg, D., Levitt, D., and Wedel, N. Treatment of relapsed or refractory acute myeloid leukemia with humanized anti-CD33 monoclonal antibody HuM195. Leukemia, 17:314, 2003.
Bains, S.K., Mone, A., Tso, J.Y., Lucas, D., Byrd, J.C., Weiner, G.J., and Green, J.M. Mitochondria control of cell death induced by anti-HLA-DR antibodies. Leukemia, 17:1357, 2003.
Heckman, K. D., Weiner, G.J., and Burns, C. P.: Persistent thrombocytopenia during remission in acute leukemia does not preclude long-term disease-free survival. Am. J. Hematol., Nov;71(3):236-237, 2002.
Jahrsdörfer B, Hartmann G, Racila E, Jackson W, Mühlenhoff L, Meinhardt G, Endres S, Krieg AM and Weiner GJ. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens. Journal of Leukocyte Biology. 69:81-88. 2001.
Kostelny, S.A., Link, B.K., Tso, J.Y., Vasquez, M., Jorgensen, B.H., Wang, H., Hall, W.C. and Weiner, G.J. Humanization and characterization of the anti-HLA-DR antibody 1D10. Int J Cancer 93(4), 556-65, 2001.
Ballas, Z.K., Krieg, A.M., Warren, T., Rasmussen, W., Davis, H.L., Waldschmidt, M., and Weiner, G.J. Divergent Therapeutic and Immunologic Effects of Oligodeoxynucleotides with Distinct CpG Motifs. J. of Immunology, 167:4878-4886, 2001.
Warren, T.L., Bhatia, S.K., Acosta, A.M., Dahle, C.E., Ratliff, T.L., Krieg, A.M. and Weiner, G.J. Antigen Presenting Cells Stimulated by CpG Oligodeoxynucleotide Enhance Activation of MHC Class I Restricted T cells. Journal of Immunology . 165:6244-51. 2000.
Hartmann, G., Weiner, G.J., Krieg, A.M. (1999) CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells. PNAS . 96, 9305-9310. 1999.
Link, B.K., Kostelny, S.A., Cole, M.S., Fusselman, W.P., Tso, J.Y. and Weiner, G.J., Anti-CD3-based Bispecific Antibody Designed for Therapy of Human B-Cell Malignancy Can Induce T-Cell Activation by Antigen-Dependent and Antigen-Independent Mechanisms. International Journal of Cancer, 77,251-256. 1998.
Rokhlin, O.W., Weiner, G.J. and Cohen, M.B. 5E10: A Prostate-Specific Surface -Reactive Monoclonal Antibody. Cancer Letters . 131, 129-136. 1998.
Liu, H., Newbrough, S.E., Bhatia, S., Dahle, C.E., Krieg, A.M. and Weiner, G.J. Immunostimulatory CpG Oligodeoxynucleotides Enhance the Immune Response to Vaccine Strategies Involving GM-CSF. Blood . 92, 3730-3736. 1998.
Weiner, M. and Weiner, G.J. The Kinetics and Dynamics of Placebo. Clinical Pharmacology and Therapeutics, 60:247-254. 1996.
Heckman, K.D., Weiner, G.J., Davis, C.S., Strauss, R.G., Jones, M.P. and Burns, C.P. Randomized Study of Prophylactic Platelet Transfusion Threshold During Induction Therapy for Adult Acute Leukemia. Journal of Clinical Oncology, 15:1143-49. 1997.
Wooldridge, J.E., Ballas, Z., Krieg, A.M. and Weiner, G.J. Immunostimulatory Oligodeoxynucleotides Containing CpG Motifs Enhance Antibody Dependent Cytotoxicity in Vitro and Improve the Efficacy of Monoclonal Antibody Therapy in Vivo. Blood . 89, 2994-2998. 1997.
Weiner, G.J., Liu, H., Wooldridge, J.E., Dahle, C.E. and Krieg, A.M. Immunostimulatory Oligodeoxynucleotides Containing the CpG Motif are Effective as Immune Adjuvants in Tumor Antigen Immunization. PNAS . 94:10833-10837. 1997.
Woolridge, J.E., Dahle, C.E. and Weiner, G.J., T-Cell Activation-Induced by Anti-CD3 x Anti-B-Cell Lymphoma Antibody is Enhanced by Pretreatment of Lymphoma Cells with Soluble CD40 Ligard Cancer. Cancer Immunology, Immunotherapy, 45, 174-179. 1997.