Department of Internal Medicine

Hematology, Oncology and Blood &  Marrow Transplantation Faculty

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James O. McNamara, Ph.D.
Assistant Professor

Dr. McNamara's research focuses on the development of RNA-based therapeutic approaches for neurological disorders.

Honors, Awards, and Organizations

• Society for Neuroscience, 1996 -
• Oligonucleotide Therapeutics Society, 2005 -

Recent Publications

1. McNamara, J.O. 2nd, et al. Stimulation of a cell-surface receptor with RNA aptamers. (In preparation), 2007.
2. McNamara, J.O. 2nd, Andrechek, E., Wang, Y., Viles, K.D., Rempel, R.E., Gilboa, E., Sullenger, B.A., Giangrande, P.H. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat. Biotech. 24(8):1005-1015, 2006.
3. Mi, J., Zhang, X., Giangrande, P.H., McNamara, J.O. 2nd, Nimjee, S.M., Sarraf-Yazdi, S., Sullenger, B.A., Clary, B.M. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. Biochem Biophys Res Commun. 338(2):956-63, 2005.

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