Department of Internal Medicine
Steven Polyak, M.D.
Dr. Polyak's clinical interests focus on Inflammatory Bowel Diseases. His research interests include the study of gene transfer to the intestine, cell and organ specific targeting and the pathophysiology of chronic intestinal inflammation. His laboratory studies adeno-associated virus mediated intestinal transduction; the role of crypt progenitor and enteroendocrine cells in long-term intestinal transgene expression; the modulation of mucosal inflammation through immunoregulatory transgene expression in animal models of colitis; and the cytokine-chemokine signatures in acute and chronic colitis. Additionally, Dr. Polyak is active in translational and clinical research including projects in imaging intestinal inflammation and characterization of IBD phenotypes. He has participated in several national clinical trials devoted to improve treatment for patients with Inflammatory Bowel Disease. Dr. Polyak has also excelled as a clinician and educator in gastroenterology. He routinely mentors medical students, residents and fellows toward careers in academic medicine. He also supports patient education through participation in local patient support groups and organizations.
Honors, Awards, and Organizations
- UF Medical Student Teaching Awards
- UF Outstanding Gastroenterology Fellowship Teacher Award
- Lamport Biomedical Research Award
- Infectious Disease and Vaccine Committee, American Society of Gene & Cell Therapy
- Crohn’s and Colitis Foundation of America
- American Society of Gene and Cell Therapy
- American Gastroenterology Association
- American College of Gastroenterology
- Diplomate, American Board of Internal Medicine
- Diplomate, American Board of Internal Medicine, Gastroenterology
- Stacy L Porvasnik, Cathryn Mah and Steven Polyak. Targeting Murine Small Bowel And Colon Through Selective Superior Mesenteric Artery Injection. Microsurgery. 2010 January, in press.
- Ahmadi A, Li Q, Muller K, Collins D, Valentine JF, Drane W, and Polyak S. The Diagnostic Value of Combined Noninvasive FDG-PET CT Enterography for Evaluation of Active Crohn’s Disease. Inflamm Bowel Dis. 2009 Nov 2.
- Davis MK, Valentine JF, Weinstein DA, and Polyak S. Antibodies to CBir1 are Associated with Glycogen Storage Disease Type Ib. J Pediatr Gastroenterol Nutr. 2009 September, in press.
- Judah JR, Hammond CJ, Polyak SF, Drane WE, and Valentine JF. The Coexistence of Crohn’s Disease and Takayasu Arteritis: Diagnosis and Treatment of Combined Disease in Three Patients. Pract. Gastroenterology. 2009 March; 33(3): 50-58.
- Ahmadi A, Polyak S, and Draganov PV. Colorectal cancer surveillance in inflammatory bowel disease: The search continues. World J Gastroenterol. 2009 Jan;15(1):61-6.
- Polyak S, Mah C, Herlihy JD, Porvasnik S, Campbell-Thompson M, Byrne BJ, and Valentine JF. Gene Delivery to Intestinal Epithelial Cells In vitro and In vivo with Recombinant Adeno-associated Virus Types 1, 2 and 5. Dig Dis Sci. 2008 May; 53(5):1261-70.