Department of Internal Medicine
M. Nedim Ince, M.D.
Dr. Ince's clinical interests include general gastroenterology with particular interest in inflammatory bowel disease. His research focuses on helminthic regulation of intestinal inflammation. His laboratory investigates the role of TLR4 and TGF-beta signaling pathways in helminthic mucosal immune modulation.
- Ince, M.N., Elliott, D.E., Setiawan, T., Blum, A., Metwali, A., Wang, Y., Urban, J.F., Weinstock, J.V. H. polygyrus induces TLR4 on murine mucosal T cells that produce TGF-beta after LPS stimulation. J Immunol, 176:726, 2006.
- Ince, M.N., Elliott, D.E. Immunologic and molecular mechanisms in inflammatory bowel disease. Surg Clin N Am, 87:681, 2007.
- Ince, M.N., Elliott, D.E., Setiawan, T., Metwali, A., Blum, A., Chen HL, Urban, J.F., Flavell, R.A., Weinstock, J.V. Role of T cell TGF-beta signaling in intestinal cytokine responses and helminthic immune modulation. Eur J Immunol. 39:1870, 2009.