Department of Internal Medicine
Gastroenterology-Hepatology Faculty
Medical School:
Case Western Reserve University
Graduate School:
London School of Economics
Residency:
Case Western Reserve University
Cleveland Metropolitan General Hospital
Fellowship:
University of Virginia
Kyle Brown, M.D., M.Sc.
Associate Professor
Director, GI-Hepatology Fellowship Training Program
Dr. Brown's clinical and research interests include Hepatology, Hepatic fibrogenesis; biology of hepatic stellate cells; role of oxidative stress in liver injury; pathogenesis of iron-induced liver injury; hemochromatosis
Recent Publications
- Brown KE, Broadhurst KA, Mathahs MM, Kladney RD, Fimmel CJ, Srivastava SK, Brunt EM. Immunodetection of aldose reductase in normal and diseased human liver. Histology and Histopathology 20:429-436, 2005.
- Brown KE, Broadhurst KA, Mathahs MM, Brunt, EM, Schmidt WN. Expression of HSP47, a collagen – specific chaperone, in normal and diseased human liver. Laboratory Investigation 85:789-797, 2005.
- Brown KE, Mathahs MM, Broadhurst KA, Weydert J. Chronic iron overload stimulates hepatocyte proliferation and cyclin D1 expression in rodent liver. Translational Research 148(2):55-62, 2006.
- Brown KE, Mathahs MM, Broadhurst KA, Coleman MC, Ridnour LA, Spitz DR. Increased telomerase activity in a rat model of iron overload: a role for altered thiol redox state? Free Radical Biology & Medicine 42:228-235, 2007.
- Bloomer SA, Brown KE, Buettner GR, Kregel KC. Dysregulation of hepatic iron with aging: implications for heat stress-induced oxidative liver injury. Am J Physiol Integr Comp Physio. doi:10.1152/ajpregu.00719.2007 (epub ahead of print, Feb. 13, 2008.)