Kyle Brown,  M.D., M.Sc.
Associate Professor
Director, GI-Hepatology Fellowship Training Program

Dr. Brown's clinical and research interests include Hepatology, Hepatic fibrogenesis; biology of hepatic stellate cells; role of oxidative stress in liver injury; pathogenesis of iron-induced liver injury; hemochromatosis

Recent Publications

1. Brown KE, Broadhurst KA, Mathahs MM, Kladney RD, Fimmel CJ, Srivastava SK, Brunt EM. Immunodetection of aldose reductase in normal and diseased human liver. Histology and Histopathology 20:429-436, 2005.
2. Brown KE, Broadhurst KA, Mathahs MM, Brunt, EM, Schmidt WN. Expression of HSP47, a collagen – specific chaperone, in normal and diseased human liver. Laboratory Investigation 85:789-797, 2005.
3. Brown KE, Mathahs MM, Broadhurst KA, Weydert J. Chronic iron overload stimulates hepatocyte proliferation and cyclin D1 expression in rodent liver. Translational Research 148(2):55-62, 2006.
4. Brown KE, Mathahs MM, Broadhurst KA, Coleman MC, Ridnour LA, Spitz DR. Increased telomerase activity in a rat model of iron overload: a role for altered thiol redox state? Free Radical Biology & Medicine 42:228-235, 2007.
5. Bloomer SA, Brown KE, Buettner GR, Kregel KC. Dysregulation of hepatic iron with aging: implications for heat stress-induced oxidative liver injury. Am J Physiol Integr Comp Physio. doi:10.1152/ajpregu.00719.2007 (epub ahead of print, Feb. 13, 2008.)

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Medical School:
Case Western Reserve University

Graduate School:
London School of Economics

Residency:
Case Western Reserve University
Cleveland Metropolitan General Hospital

Fellowship:
University of Virginia