Department of Internal Medicine
Cardiovascular Medicine Faculty
Graduate School:
Wuhan University, China
Tongji Medical University, WuHan, China
Postdoctoral Fellowship:
University of Montreal, Canada
Vanderbilt University
Yuejin Wu, Ph.D.
Associate Professor
Dr. Wu's reseach interests include the electrophysiological properties of heart cells, the role of calmodulin kinase II (CaMKII) in regulating intracellular calcium and interacting with the other calcium regulating proteins in heart cells, and the proarrhythmia mechanism of over active CaMKII and inhibition of CaMKII as a way to antiarrhythmia.
Select Publications
- Grueter CE, Abiria SA, Dzhura I, Wu Y, Ham AJL, Mohler PJ, Anderson ME, Colbran RJ. L-type Ca2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII. Molecular Cell, 2006; 23(5):641-650.
- Le Scouarnec S, Bhasin N, Vieyres C, Hund TJ, Cunha SR, Koval O, Marionneau C, Chen B, Wu Y, Demolombe S, Song LS, Le Marec H, Probst V, Schott JJ, Anderson ME, Mohler PJ. Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease. Proc Natl Acad Sci USA. 2008;105(40):15617-22.
- Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke WJ, Sarma S, Grumbach IM, Wehrens XHT, Mohler PJ, Song LS, Anderson ME. Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proc Natl Acad Sci U S A. 2009>; published online before print March 10, 2009.