Department of Internal Medicine

Cardiovascular Medicine Faculty

Madhu Singh

Graduate School:
University of Alberta, Canada

Postdoctoral Fellowship:
University of Wisconsin
Vanderbilt University, Nashville

Madhu Singh, Ph.D.
Research Assistant Professor

Dr. Singh's research interests include the role of Ca2+/Calmodulin kinase in inflammatory signaling in post-injury heart, gene regulation in cardiac diseases, and innate immunity and cardiac disease.

Honors, Awards, and Organizations

Recent Publications

  1. Singh, M.V.; Kapoun, A.; Higgins, L.; Kutschke, W.; Thurman, J.M.; Zhang, R.; Singh, M.; Yang, J.; Guan, X.; Lowe, J.; Weiss, R.M.; Zimmerman, K.; Yull, F.E.; Blackwell, T.S.; Mohler, P.J.; Anderson, M.E. 2009. Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart. J. Clinical Invest. 119(4): 986-996.
  2. Wu, Y.; Gao, Z.; Chen, B.; Koval, O. M. Koval, Singh, M.V.; Guan, X.; Hund,T.J.; Kutschke,W.J.;Sarma,S.; Grumbach, I.M.; Wehrens, X.H.T.; Mohler, P.J.; Song, L.-S.; Anderson, M.E. 2009. Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proceed. Natl. Acad. Sci. USA. (In Press).
  3. Werdich, A.A.; Lima, E.A.; Dzhura, I.; Singh, M.V.; Li, J.; Anderson, M.E.; Baudenbacher, F.J. 2008. Differential effects of phospholamban and Ca2+/calmodulin-dependent kinase II on Ca2+ uptake and release in isolated cardiac myocytes at physiological pacing rates. Am. J. Physiology. Heart Circ. Physiol., 294 (5): H2352-2362.
  4. Khoo M.S.C.; Li, Jingdong; Singh, M.V.*; Yang, Y.; Kannankeril, P.; Wu, Y.; Grueter, C.E.; Guan, X.; Oddis, C.V.; Zhang, R.; Mendes, L.; Ni, G.; Madu, E.; Yang, J.; Bass, M.; Gomez, R.J.; Wadzinski, B.E.; Olson, E.N.; Colbran, R.J.; Anderson, M.E. 2006. Death, Cardiac Dysfunction and Arrhythmias are Increased by Calmodulin Kinase II in Calcineurin Cardiomyopathy, Circulation,114: 1352-135.
  5. Singh, M.V.; Bland, C.E.; Weil, P.A. 2004. Molecular genetic characterization of a Taf1p domain essential for yeast TFIID assembly. Molecular and Cellular Biology, 24: 4929-4942.
  6. Singh, M.V.; Weil, P.A. 2002. A method for plasmid purification directly from yeast. Analytical Biochemistry, 307: 13-17.
  7. Singh, M.V.; Jimbow, K.  1998.  Melanin synthesis and growth retardation in glioma cells by tyrosinase transfection.  Melanoma Research, 8:493-498.
  8. Singh, M.V.; Ntambi, J.M.  1998. Nuclear factor 1 is essential for the expression of stearoyl coA desaturase 1 gene during preadipocyte differentiation.  Biochim. Biophys. Acta:  Gene Structure and Expression, 1398: 148-156.
  9. Singh, M.V.; Malhotra, S.K. 1996.  The Gap Junction.  In: Advances in Structural Biology, Vol.3 (S.K. Malhotra, ed.).  N.Y., Jai Press, pp. 41-74.

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