Department of Internal Medicine
Cardiovascular Medicine Faculty
Medical School:
University of Illinois
Residency:
The University of Iowa
Fellowship:
The University of Iowa
James B. Martins, M.D.
Professor
Director of Cardiovascular Medicine, VAMC
Director, Arrhythmia Service
Director, Clinical Cardiac Electrophysiology Training Program
Dr. Martins' clinical interests focus on the diagnosis and treatment of arrhythmias. His research interests include autonomic control of ventricular muscle and Purkinje electrophysiology in ischemia.
Honors, Awards, and Organizations
- American Heart Association
- American Physiological Society
- Central Society for Clinical Research
- North American Society for Pacing and Electrophysiology
- Alpha Omega Alpha
- Clinical Scientist Award, American Heart Association, 1979-84
- Established Investigator Award, American Heart Association, 1986-91
- Humanism in Medicine Award (Health Care Foundation of Medicine of New Jersey) for the Iowa College of Medicine, 1999
- 1st Dr. Irving George Pesek Humanitarian Award, 2004
Recent Publications
- Kwofie, M.A., Chaudhary, A.K., and Martins, J.B.: Association Among Intracardiac T-wave Alternans, Ischemia, and Spontaneous Ventricular Arrhythmias After Coronary Artery Occlusion in a Canine Model. Transl. Res., In Press, 2011.
- Gao, Z., Singh, M.V., Hall, D.D., Koval, O.M., Luczak, E.D., Joiner, M.L., Chen, B., Wu, Y., Chaudhary, A.K., Martins, J.B., Hund, T.J., Mohler, P.J., Song, L.S., and Anderson, M.E.: Catecholamine-independent Heart Rate Increases Require Ca2+/calmodulin-dependent Protein Kinase II. Circ. Arrhythm. Electrophysiol., 4(3):379-87, 2011.
- Gao, Z., Chen, B., Joiner, M.L., Wu, Y., Guan, X., Koval, O.M., Chaudhary, A.K., Cunha, S.R., Mohler, P.J., Martins, J.B., Song, L.S., and Anderson ME: I(f) and SR Ca(2+) Release Both Contribute to Pacemaker Activity in Canine Sinoatrial Node Cells. J. Mol. Cell Cardiol., 49(1):33-40, 2010.
- Xing, D., Chaudhary, A.K., Miller, F.J., and Martins, J.B.: Free Radical Scavenger Specifically Prevents Ischemic Focal Ventricular Tachycardia. Heart Rhythm, 6:530-6, 2009.
- Gopinathannair, R., Chaudhary, A.K., Xing, D., Ely, D., Zheng, W., and Martins, J.B.: Angiotensin II Effects on Ischemic Focal Ventricular Tachycardia are Predominantly Mediated Through Myocardial AT(2) Receptor. Am. J. Physiol., 297(5):H1889-98, 2009.
- Grippo, A. J., Santos, C. M., Johnson, R. F., Beltz, T. G., Martins, J. B., Felder R. B., and Johnson, A. K. Increased Susceptibility to Ventricular Arrhythmias in a Rodent Model of Experimental Depression. Am. J. Physiol., 286:H619-H626, 2004.
- Klein, R.C., Raitt, M.H., Wilkoff, B.L., Beckman, K.J., Coromilas, J., Wyse, D.G., Friedman, P.L., Martins, J., Epstein, A.E., Hallstrom, A.P., Ledingham, R.B., Belco, K.M., Greene, H.L., and the AVID Investigators: Analysis of Implantable Cardioverter Defibrillator Therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial. J. Cardiovasc. Electrophysiol. 14(9):940-948, 2003.
- Raitt, M.H., Klein, R.C., Wyse, D.G., Wilkoff, B.L., Beckman, K., Epstein, A.E., Coromilas, J., Friedman, P.L., Martins, J., Ledingham, R.B., Greene, H.L., and Antiarrhythmics Versus Implantable Defibrillators Investigators: Comparison of Arrhythmia Recurrence in Patients Presenting with Ventricular Fibrillation Versus Ventricular Tachycardia in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. Am. J. Cardiol. 91(7):812-816, 2003.
- Arnar, D.O. and Martins, J.B.: Purkinje Involvement in Arrhythmias After Coronary Artery Reperfusion. Am. J. Physiol. H1189-H1196, 2002.
- Cai, J.J., Morgan, D.A., Haynes, W.G., Martins, J.B., and Lee, H.C.: a 2 -Adrenergic Stimulation in Protective Against Ischemia-Reperfusion-Induced Ventricular Arrhythmias In Vivo. Am. J. Physiol. 283(6):H2606-H2611, 2002.
- Xing, D., Kjølbye, A.L., Nielsen, M.S., Petersen, J.S., Harlow, K.W., Holstein-Rathlow, N.H., and Martins, J.B.: ZP123 Increases Gap Junctional Conductance and Prevents Reentrant Ventricular Tachycardia During Myocardial Ischemia in Open Chest Dogs. J. Cardiovasc. Electrophysiol. 14:510-520, 2003.