Department of Internal Medicine
Cardiovascular Medicine Faculty
Medical School:
The University of Iowa
Residency:
University of Texas
Southwestern Medical Center
Fellowship:
The University of Iowa
Francis J. Miller, Jr., M.D.
Associate Professor
Dr. Miller's clinical interests include cardiology inpatient services and diagnostic cardiac catheterization. His research is directed at understanding molecular and cellular mechanisms involved in redox-mediated signaling by NADPH oxidases in the pathophysiology of vascular disease.
Honors, Awards, and Organizations
- Board Certification, Internal Medicine
- Board Certification, Cardiovascular Diseases
- American Physiological Society, Cardiovascular Section
- North American Vascular Biology Organization
- American Heart Association, Council on Arteriosclerosis, Thrombosis, and Vascular Biology; Council on Basic Cardiovascular Sciences
- Chair, Midwestern Section of American Federation for Medical Research, 2007-08
- Society for Free Radical Biology and Medicine
- Editorial Board, Arteriosclerosis, Thrombosis, and Vascular Biology, 2002-
- Editorial Board, American Journal of Physiology, Heart and Circulatory Physiology, 1999-04
- Peer Review Committees for the NIH, AHA and VA
- Associate Editor, Cardiovascular Therapeutics, 2010-
- President, American Federation for Medical Research, 2010-11
Recent Publications
- Miller FJ Jr, Filali M, Huss GJ, Stanic B, Chamseddine A, Barna TJ, Lamb FS. Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3. Circ Res. 2007, 101:663-71. PMID: 17673675.
- Lamb FS, Moreland JG, Miller FJ Jr. Electrophysiology of reactive oxygen production in signaling endosomes. Antioxid Redox Signal. 2009, 11:1335-47. PMID: 19207039.
- Miller FJ Jr, Chu X, Stanic B, Tian X, Sharma RV, Davisson RL, Lamb FS. A differential role for endocytosis in receptor-mediated activation of Nox1. Antioxid Redox Signal. 2010, 12:583-93. PMID: 19737091.
- Stanic B, Katsuyama M, Miller FJ Jr. An Oxidized Extracellular Oxidation-Reduction State Increases Nox1 Expression and Proliferation in Vascular Smooth Muscle Cells Via Epidermal Growth Factor Receptor Activation. Arterioscler Thromb Vasc Biol. 2010: 30:2234-2241. PMID: 20814013.
- Chu X, Filali M, Stanic B, Takapoo M, Sheehan A, Bhalla R, Lamb FS, Miller FJ Jr. A Critical Role for ClC-3 in Smooth Muscle Activation and Neotintima Formation. Arterioscler Thromb Vasc Biol. 2011. 31:345-51. PMID:21071705.
- Sheehan AL, Carrell S, Johnson B, Stanic B, Banfi B, Miller FJ Jr. Role for Nox1 NADPH oxidase in atherosclerosis. Atherosclerosis, 2011, In Press. PMID: 21411092.
Links of Interest