Curt D. Sigmund, Ph.D.
Professor of Medicine and Molecular Physiology and Biophysics
Dr. Sigmund's research interests focus on mechanisms of blood pressure regulation by the renin-angiotensin system. He utilizes a combination of molecular biological and physiological approaches to the problem. Currently, Dr. Sigmund is interested in constructing transgenic animal models of hypertension and in examining the molecular biology of the human renin-angiotensin system in transgenic mice.
Honors, Awards, and Organizations
- American Association for the Advancement of Science
- American Heart Association
- Council on High Blood Pressure Research
- American Physiological Society
Recent Publications
- Cvetkovic, B., Keen, H.L., Zhang, X., Davis, D., Yang, B., and Sigmund, C.D.: Physiological Significance of Two Common Haplotypes of Human Angiotensinogen Using Gene Targeting in the Mouse. Physiological Genomics 11: 253-262, 2002.
- Liu, X., Huang, X., Sigmund, C.D.: Identification of A Nuclear Orphan Receptor (Ear2) As A Negative Regulator of Renin Gene Transcription. Circulation Research 92: 1033-1040, 2003.
- Morimoto, S., Cassell, M.D., and Sigmund, C.D. Glial- and neuronal-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. J. Biol. Chem. 277:33235-33241, 2002.
- Click here for additional publications.
|
Graduate School:
Molecular and Cellular Biology, State University of New York at Buffalo
Fellowship:
Roswell Park Cancer Institute, Buffalo, New York |
